From 80e339518f74e3b2fdc228ae749ddc1f5594f42c Mon Sep 17 00:00:00 2001 From: Krishna Udaiwal Date: Sun, 30 Aug 2026 21:47:49 -0400 Subject: [PATCH] Restore curation the editor's stale saves reverted, and fail CI on deletions The ARI editor writes the whole ontology from a copy loaded when the session started, so each save reverts anything merged into the branch since. 295fb23 deleted a confirmation three seconds after 17e616c merged it in cleanly; 0f03b91, labelled a review of one disease, changed 453 lines. Restores 95 changelog entries, 10 synonyms and 17 clinical subtypes from the merged history, plus 208 synonyms and 57 clinical subtypes from PR #69, the last commit before the 17 August cliff. Stores 30 confirmed cross-references that had never been written to a disease, including the MONDO and Orphanet terms linikujp confirmed for Hemophilia B Leyden on 21 August. Re-applies the ICD-9 retirement, the MONDO de-prefixing and the ICD-10 range removal, all overwritten the day after they landed. Cross-references are now derived from the mapping set rather than from either snapshot: flagged ids are dropped, confirmed ids stored. Also corrects the inverted OMOP judgment for Multiple sclerosis in ari.equivalencies.tsv and removes three judgments recorded twice, keeping the earlier author each time. Validate mappings ran with --since BASE_SHA and reported only rows a branch added, so a save that deleted 385 lines passed clean. check_deletions now compares against the pull request's base and fails on records removed without a curator judgment behind them; replayed against 0f03b91 it reports 24 errors. Ports the sssom comment-column header fix so the weekly audit stops skipping every SSSOM row check in silence, and accepts the ISO timestamp the app writes. The app-side fixes -- saving a diff instead of a snapshot, and storing an id at confirmation time -- belong in KrishnaTO/ARI-metadata-manager and are not here. Audit: 66 errors -> 0 errors, 6 warnings. confirmed-not-stored: 30 -> 0. Co-Authored-By: Claude Opus 5 --- .github/scripts/validate_mappings.py | 169 +++++- changelog.md | 67 +++ mappings/ari.equivalencies.tsv | 7 +- mappings/ari.sssom.tsv | 3 - ontologies/ari_t1d.owl | 803 +++++++++++++++++++++------ 5 files changed, 854 insertions(+), 195 deletions(-) diff --git a/.github/scripts/validate_mappings.py b/.github/scripts/validate_mappings.py index c3f3e34..4d1f0d9 100644 --- a/.github/scripts/validate_mappings.py +++ b/.github/scripts/validate_mappings.py @@ -47,6 +47,7 @@ "mapping_justification", "author_id", "mapping_date", + "comment", ] EQUIV_COLUMNS = [ "source_prefix", @@ -59,6 +60,13 @@ "source", ] +# A reversed judgment keeps BOTH rows: the editor app annotates the withdrawn one +# in `comment` instead of deleting it, so a consumer can see which of two +# contradictory rows was withdrawn without reimplementing the ordering. Kept in +# step with `SUPERSEDED_PREFIX` in the app's `app/sssom_service.py`. Only rows +# without this marker count as live judgments. +SUPERSEDED_MARKER = "Superseded by the " + ALLOWED_PREDICATES = {"skos:exactMatch"} ALLOWED_JUSTIFICATIONS = {"semapv:ManualMappingCuration", "semapv:LexicalMatching"} ALLOWED_MODIFIERS = {"", "Not"} @@ -133,7 +141,10 @@ ARI_SUBJECT_RE = re.compile(r"ARI:\d{4,7}") AUTHOR_RE = re.compile(r"github:[A-Za-z0-9](?:[A-Za-z0-9-]{0,37}[A-Za-z0-9])?") -DATE_RE = re.compile(r"\d{4}-\d{2}-\d{2}") +# SSSOM types `mapping_date` as a date, but the editor app publishes a full ISO +# 8601 timestamp because two judgments on one pair in one day need an order. +# Both are accepted; the date part is what the check is really about. +DATE_RE = re.compile(r"\d{4}-\d{2}-\d{2}(?:T\d{2}:\d{2}:\d{2}(?:Z|[+-]\d{2}:\d{2})?)?") ICD9_RE = re.compile(r"\d{2,3}(\.\d{1,2})?") ENTITY_OPEN_RE = re.compile(r" dict[str, Disease] | None: except ElementTree.ParseError as exc: report.error("ontology-not-well-formed", ONTOLOGY_PATH, 0, f"OWL/XML does not parse: {exc}.") return None + return parse_ontology(text, report) + +def parse_ontology(text: str, report: Report | None = None) -> dict[str, Disease]: + """Diseases keyed by ARI id, from already-read OWL text.""" diseases: dict[str, Disease] = {} current: dict | None = None for index, line in enumerate(text.replace("\r\n", "\n").split("\n"), start=1): @@ -307,12 +322,14 @@ def load_ontology(report: Report) -> dict[str, Disease] | None: ari_id = ids[0][0] if ids else None if ari_id and ari_id.startswith("ARI:"): if ari_id in diseases: - report.error( - "duplicate-ari-id", - ONTOLOGY_PATH, - ids[0][1], - f"{ari_id} is used by more than one entity, so mappings for it are ambiguous.", - ) + if report is not None: + report.error( + "duplicate-ari-id", + ONTOLOGY_PATH, + ids[0][1], + f"{ari_id} is used by more than one entity, so mappings for it " + "are ambiguous.", + ) else: diseases[ari_id] = Disease(ari_id, current["label"], dict(current["annotations"])) current = None @@ -408,9 +425,11 @@ def check_sssom_rows(rows: list[Row], report: Report) -> None: mapping_date = fields["mapping_date"] if not DATE_RE.fullmatch(mapping_date): report.error( - "date-format", SSSOM_PATH, line, f"`mapping_date` {mapping_date!r} is not ISO YYYY-MM-DD." + "date-format", SSSOM_PATH, line, f"`mapping_date` {mapping_date!r} is not an ISO 8601 date or timestamp." ) - elif mapping_date > today: + elif mapping_date[:10] > today: + # Compare the date part only: a timestamp sorts after the bare date it + # falls on, so the whole string would read as tomorrow. report.error( "date-future", SSSOM_PATH, @@ -431,17 +450,20 @@ def check_sssom_rows(rows: list[Row], report: Report) -> None: ) else: seen[key] = line - modifiers_by_pair[(subject, object_id)][modifier] = line + superseded = fields["comment"].startswith(SUPERSEDED_MARKER) + modifiers_by_pair[(subject, object_id)][modifier] = (line, superseded) for (subject, object_id), by_modifier in modifiers_by_pair.items(): - if len(by_modifier) > 1: - lines = ", ".join(str(by_modifier[m]) for m in sorted(by_modifier)) + live = sorted(line for line, superseded in by_modifier.values() if not superseded) + if len(live) > 1: + lines = ", ".join(str(line) for line in live) report.error( "contradiction", SSSOM_PATH, - min(by_modifier.values()), + live[0], f"{subject} -> {object_id} is recorded as both confirmed and flagged-wrong " - f"(lines {lines}). One of the two judgments has to go.", + f"(lines {lines}) with neither row marked superseded. A reversal must annotate " + f"the withdrawn row in `comment`; otherwise one of the two judgments has to go.", ) for subject, by_label in labels.items(): @@ -878,11 +900,116 @@ def baseline_lines(ref: str, path: str) -> set[str] | None: return set(result.stdout.decode("utf-8", "replace").replace("\r\n", "\n").split("\n")) -def current_lines(path: str) -> list[str]: +def current_text(path: str) -> str: full = os.path.join(REPO_ROOT, path) if not os.path.exists(full): - return [] - return open(full, encoding="utf-8", errors="replace").read().replace("\r\n", "\n").split("\n") + return "" + return open(full, encoding="utf-8", errors="replace").read().replace("\r\n", "\n") + + +def current_lines(path: str) -> list[str]: + return current_text(path).split("\n") + + +# Curation records that only ever accumulate. Nothing a curator decides removes +# one, so a branch that drops one is reverting somebody rather than reviewing. +APPEND_ONLY_PROPERTIES = { + "ARI_Synonym": "synonym", + "ARI_ClinicalSubtype": "clinical subtype", + "ARI_ChangeLog": "changelog entry", +} +# How many deleted values to name before the message just gives the count. +DELETION_SAMPLE = 3 + + +def _values(disease: Disease, prop: str) -> set[str]: + out = set() + for value, _ in disease.annotations.get(prop, []): + out.update(part.strip() for part in value.split(",") if part.strip()) + return out + + +def summarise(values: set[str]) -> str: + shown = sorted(values)[:DELETION_SAMPLE] + rendered = ", ".join(repr(v if len(v) <= 60 else v[:57] + "...") for v in shown) + extra = len(values) - len(shown) + return rendered + (f" and {extra} more" if extra else "") + + +def check_deletions(ref: str, sssom_rows: list[Row], report: Report) -> None: + """Report curation this branch removes from the ontology without reviewing it. + + The row checks only see rows that exist, so a save that reverts somebody + else's work passes them all. This is the check that fails on absence. + + A cross-reference may legitimately go: flagging one wrong on the review page + is exactly how a bad code is retired, and that judgment is in the mapping set. + Anything else -- a synonym, a subtype, a changelog entry, or an id no curator + ruled against -- has no decision behind its removal. + """ + result = subprocess.run( + ["git", "show", f"{ref}:{ONTOLOGY_PATH}"], + cwd=REPO_ROOT, + capture_output=True, + ) + if result.returncode != 0: + return # the ontology is new on this branch; nothing to have deleted + before = parse_ontology(result.stdout.decode("utf-8", "replace")) + after = parse_ontology(current_text(ONTOLOGY_PATH)) + if not before or not after: + return + + flagged = collections.defaultdict(set) + for row in sssom_rows: + if row.fields["predicate_modifier"].strip() != "Not": + continue + object_id = row.fields["object_id"].strip() + if ":" in object_id: + prefix, local = object_id.split(":", 1) + flagged[(row.fields["subject_id"].strip(), prefix)].add(local) + + for ari_id, was in sorted(before.items()): + now = after.get(ari_id) + if now is None: + report.error( + "disease-deleted", + ONTOLOGY_PATH, + 0, + f"{ari_id} ({was.label!r}) is in {ref} but not in this branch. A disease is " + "retired by setting ARI_Obsolete, never by deleting the individual.", + ) + continue + + for prop, noun in APPEND_ONLY_PROPERTIES.items(): + lost = _values(was, prop) - _values(now, prop) + if lost: + report.error( + "record-deleted", + ONTOLOGY_PATH, + 0, + f"{ari_id} loses {len(lost)} {noun}(s) this branch did not add: " + f"{summarise(lost)}. {prop} is an append-only record — restore the " + f"value, or say in review why it is being withdrawn.", + ) + + for prefix, properties in ONTOLOGY_PROPERTIES.items(): + was_ids = set().union(*(_values(was, p) for p in properties)) + now_ids = set().union(*(_values(now, p) for p in properties)) + lost = was_ids - now_ids - flagged[(ari_id, prefix)] + # A value that is not a well-formed identifier for its vocabulary was + # never a usable cross-reference: an ICD-9 code under ICD-10, a range, + # a doubly-prefixed CURIE. Dropping or re-spelling one is a repair, and + # the shape checks already report it if it is still there. + lost = {value for value in lost if ID_PATTERNS[prefix].fullmatch(value)} + if lost: + report.error( + "xref-deleted", + ONTOLOGY_PATH, + 0, + f"{ari_id} loses {prefix} {summarise(lost)} with no matching " + f"`predicate_modifier: Not` row in {SSSOM_PATH}. Flag the id wrong on the " + "review page so the judgment is recorded, or restore it.", + ) def filter_to_changes(findings: list[Finding], ref: str) -> list[Finding]: @@ -983,7 +1110,13 @@ def main() -> int: scope = "whole repository" if args.since: findings = filter_to_changes(findings, args.since) - scope = f"lines changed since `{args.since}`" + # Deletions are reported after the diff filter, not through it: the filter + # keeps findings that sit on a changed line, and a deleted record has no + # line left to sit on. + deletions = Report() + check_deletions(args.since, sssom_rows, deletions) + findings = sorted(findings + deletions.findings, key=Finding.sort_key) + scope = f"changes since `{args.since}`" for finding in findings: if args.annotate: diff --git a/changelog.md b/changelog.md index c64935c..71ddc6f 100644 --- a/changelog.md +++ b/changelog.md @@ -1,5 +1,72 @@ # Changelog +## restore-overwritten-curation + +- Restores curation that the editor app's saves reverted, and re-applies the cleanups they + undid. The audit goes from **66 errors** back to **0 errors, 6 warnings**, and every + confirmed mapping is now stored on its disease — `confirmed-not-stored` is at zero for the + first time since the check was written. +- **The cause is not curation.** An editor save writes the whole ontology from a copy loaded + when the session started, so it reverts anything merged into the branch since. `0f03b91` is + labelled a review of one disease, ARI:0001143, and changed 453 lines. `295fb23` deleted a + confirmation three seconds after `17e616c` merged it in cleanly. Two curators' saves on + 17 August landed on byte-identical stale content, which points at a shared server-side copy + rather than per-user browser state. **The fix for that belongs in + [`KrishnaTO/ARI-metadata-manager`](https://github.com/KrishnaTO/ARI-metadata-manager) and is + not in this change** — until a save applies a diff instead of a snapshot, the next publish + can revert this one. +- **Restored 95 changelog entries, 10 synonyms and 17 clinical subtypes** from the merged + history, plus **208 synonyms and 57 clinical subtypes** from PR #69, the last commit before + the 17 August cliff. Only commits reachable from `main` were read, so nothing arrives from a + branch that was never accepted. Synonyms 490 → 708, clinical subtypes 355 → 429, recorded + cross-reference reviews 194 → 305. Verified afterwards: every distinct (disease, author, + review) record that ever reached `main` is present, and none was invented — 603 of 603. +- **Stored 30 confirmed cross-references that had never been written to a disease**, across + 16 diseases — 12 MONDO, 10 Orphanet, 3 UMLS and one each of DOID, NCIt, MeSH, ICD-10 and + OMIM. Confirming a term only ever affirmed an id the disease already held, so confirming one + the registry lacked recorded a judgment with no data behind it. That skews to MONDO and + Orphanet because the original ARI import carried almost nothing from either. Hemophilia B + Leyden (ARI:0001098) now holds MONDO:0850054 and ORPHA:617930, confirmed by linikujp on + 21 August and absent ever since. **Writing the id at confirmation time is also an app-side + fix and is not in this change.** +- **Re-applied the reverted cleanups**: 61 ICD-9 codes filed under `ARI_ICD10`, the two + `MONDO:`-prefixed values on ARI:0001080 and ARI:0002, and the ranges `I00-I02` and + `390-392.99` on Rheumatic fever. All three had landed on 16 August and were overwritten the + next day. Cross-references are now derived from the mapping set rather than from either + snapshot: a value flagged `predicate_modifier: Not` is dropped, a confirmed one is stored. + That reproduces aaronabend's own correction in `1f18f16` — Multiple sclerosis keeps the + single OMOP concept 4027727 and SNOMED 24700007 — without special-casing it. +- **Fixed three mapping-file errors that had been invisible.** `ari.equivalencies.tsv` and + `ari.sssom.tsv` disagreed about which OMOP concept is Multiple sclerosis; the equivalencies + rows for 374919 and 4027727 were the inverted pair and now match the SSSOM side and the + ontology. Three judgments were recorded twice — a curator reviewed a pair, the record was + wiped, the pair resurfaced as unreviewed, and a second curator confirmed the same terms + again. The first judgment is kept in each case, so linikujp keeps the credit for + ARI:0001019 that was taken once already. +- **`Validate mappings` can now fail on absence.** It ran with `--since BASE_SHA` and reported + only rows a branch added or rewrote, so a save that deleted 385 lines passed clean. The new + `check_deletions` compares the ontology against the pull request's base and reports + `record-deleted`, `xref-deleted` and `disease-deleted`. A cross-reference may still go — that + is what flagging one wrong on the review page does, and the judgment is in the mapping set — + but a synonym, a subtype, a changelog entry or an id no curator ruled against may not. + Removing a malformed value is exempt, so repairing an ICD-9 code or a doubled prefix is not + mistaken for a reversal. Replayed against `0f03b91`, the commit that started this: **24 + errors**, where CI previously reported none. +- **Restored the weekly audit's sight.** The editor began writing a tenth `comment` column into + `ari.sssom.tsv`; the header check rejected it, `split_rows` returned nothing, and every SSSOM + row check was skipped in silence — including the two that exist to catch precisely this. Ports + the header fix from `fix/sssom-comment-column` (validator only, none of that branch's data), + and widens `mapping_date` to accept the ISO 8601 timestamp the app writes: all 548 rows carry + one, and a timestamp sorts after the bare date it falls on, which made every row today read as + tomorrow. +- Two things are deliberately left alone. Some diseases now carry the same review recorded more + than once under different timestamps, an artifact of the app re-recording a judgment whose + record had been wiped; collapsing them is a curator's call and does not belong in a + restoration, particularly one that adds a rule saying `ARI_ChangeLog` is append-only. And + Chronic Lyme disease (ARI:0001065) now holds four OMOP concepts — two curated on 16 August, + two the stale save put back — with no judgment on any of them; **that pair needs a curator.** +- The six remaining warnings are the standing `dxcode-without-snomed` debt, unchanged. + ## disease-target-mapping-sheet - Added `data/4-reports/8_Disease_Target_Mappings.xlsx`: one row per (disease, target diff --git a/mappings/ari.equivalencies.tsv b/mappings/ari.equivalencies.tsv index 25b6bad..a692f64 100644 --- a/mappings/ari.equivalencies.tsv +++ b/mappings/ari.equivalencies.tsv @@ -507,8 +507,6 @@ ARI 0001028 Autoimmune encephalitis skos:exactMatch MONDO 0020640 manual github: ARI 0001019 Antisynthetase syndrome skos:exactMatch SNOMEDCT 445187004 manual github:aaronabend ARI 0001019 Antisynthetase syndrome skos:exactMatch omop 40482477 manual github:aaronabend ARI 0001019 Antisynthetase syndrome skos:exactMatch DOID 0080744 manual github:aaronabend -ARI 0001019 Antisynthetase syndrome skos:exactMatch MONDO 0019344 manual github:aaronabend -ARI 0001019 Antisynthetase syndrome skos:exactMatch ORPHA 81 manual github:aaronabend ARI 0001135 Multiple sclerosis skos:exactMatch DOID 2377 manual github:aaronabend ARI 0001135 Multiple sclerosis skos:exactMatch MONDO 0005301 manual github:aaronabend ARI 0001135 Multiple sclerosis skos:exactMatch ncit C3243 manual github:aaronabend @@ -517,11 +515,11 @@ ARI 0001135 Multiple sclerosis skos:exactMatch SNOMEDCT 426373005 manual-negativ ARI 0001135 Multiple sclerosis skos:exactMatch SNOMEDCT 428700003 manual-negative github:aaronabend ARI 0001135 Multiple sclerosis skos:exactMatch SNOMEDCT 49692006 manual-negative github:aaronabend ARI 0001135 Multiple sclerosis skos:exactMatch SNOMEDCT 24700007 manual github:aaronabend -ARI 0001135 Multiple sclerosis skos:exactMatch omop 374919 manual github:aaronabend +ARI 0001135 Multiple sclerosis skos:exactMatch omop 374919 manual-negative github:aaronabend ARI 0001135 Multiple sclerosis skos:exactMatch omop 4178929 manual-negative github:aaronabend ARI 0001135 Multiple sclerosis skos:exactMatch omop 4145049 manual-negative github:aaronabend ARI 0001135 Multiple sclerosis skos:exactMatch omop 376970 manual-negative github:aaronabend -ARI 0001135 Multiple sclerosis skos:exactMatch omop 4027727 manual-negative github:aaronabend +ARI 0001135 Multiple sclerosis skos:exactMatch omop 4027727 manual github:aaronabend ARI 0001028 Autoimmune encephalitis skos:exactMatch icd10cm NoTermFound manual-absent github:aaronabend ARI 0001098 Hemophilia B Leyden skos:exactMatch MONDO 0850054 manual github:linikujp ARI 0001098 Hemophilia B Leyden skos:exactMatch ORPHA 617930 manual github:linikujp @@ -529,7 +527,6 @@ ARI 0001090 Essential mixed cryoglobulinemia skos:exactMatch MONDO 0007407 manua ARI 0001090 Essential mixed cryoglobulinemia skos:exactMatch ORPHA 91138 manual github:linikujp ARI 0001019 Antisynthetase syndrome skos:exactMatch MONDO 0019344 manual github:linikujp ARI 0001019 Antisynthetase syndrome skos:exactMatch ORPHA 81 manual github:linikujp -ARI 0001056 Birdshot chorioretinopathy skos:exactMatch ORPHA 179 manual github:KrishnaTO ARI 0001056 Birdshot chorioretinopathy skos:exactMatch omop 4334133 manual github:KrishnaTO ARI 0001002 Acquired hemophilia skos:exactMatch MONDO 0019139 manual github:KrishnaTO ARI 0001002 Acquired hemophilia skos:exactMatch ncit C197822 manual github:KrishnaTO diff --git a/mappings/ari.sssom.tsv b/mappings/ari.sssom.tsv index 4d884f1..0e0ceda 100644 --- a/mappings/ari.sssom.tsv +++ b/mappings/ari.sssom.tsv @@ -521,15 +521,12 @@ ARI:0001143 Neuromyelitis optica skos:exactMatch icd10cm:G36.0 icd10cm semapv:M ARI:0001143 Neuromyelitis optica skos:exactMatch ORPHA:71211 ORPHA semapv:ManualMappingCuration github:aaronabend 2026-08-17T00:00:00+00:00 ARI:0001143 Neuromyelitis optica skos:exactMatch mesh:D009471 mesh semapv:ManualMappingCuration github:aaronabend 2026-08-17T00:00:00+00:00 ARI:0001143 Neuromyelitis optica skos:exactMatch sssom:NoTermFound OMIM semapv:ManualMappingCuration github:aaronabend 2026-08-17T00:00:00+00:00 -ARI:0001056 Birdshot chorioretinopathy skos:exactMatch ORPHA:179 ORPHA semapv:ManualMappingCuration github:KrishnaTO 2026-08-30T20:37:59+00:00 ARI:0001028 Autoimmune encephalitis skos:exactMatch omop:4318558 omop semapv:ManualMappingCuration github:aaronabend 2026-08-27T00:00:00+00:00 ARI:0001028 Autoimmune encephalitis skos:exactMatch SNOMEDCT:95643007 SNOMEDCT semapv:ManualMappingCuration github:aaronabend 2026-08-27T00:00:00+00:00 ARI:0001028 Autoimmune encephalitis skos:exactMatch MONDO:0020640 MONDO semapv:ManualMappingCuration github:aaronabend 2026-08-27T00:00:00+00:00 ARI:0001019 Antisynthetase syndrome skos:exactMatch SNOMEDCT:445187004 SNOMEDCT semapv:ManualMappingCuration github:aaronabend 2026-08-27T00:00:00+00:00 ARI:0001019 Antisynthetase syndrome skos:exactMatch omop:40482477 omop semapv:ManualMappingCuration github:aaronabend 2026-08-27T00:00:00+00:00 ARI:0001019 Antisynthetase syndrome skos:exactMatch DOID:0080744 DOID semapv:ManualMappingCuration github:aaronabend 2026-08-27T00:00:00+00:00 -ARI:0001019 Antisynthetase syndrome skos:exactMatch MONDO:0019344 MONDO semapv:ManualMappingCuration github:aaronabend 2026-08-27T00:00:00+00:00 -ARI:0001019 Antisynthetase syndrome skos:exactMatch ORPHA:81 ORPHA semapv:ManualMappingCuration github:aaronabend 2026-08-27T00:00:00+00:00 ARI:0001135 Multiple sclerosis skos:exactMatch DOID:2377 DOID semapv:ManualMappingCuration github:aaronabend 2026-08-27T00:00:00+00:00 ARI:0001135 Multiple sclerosis skos:exactMatch MONDO:0005301 MONDO semapv:ManualMappingCuration github:aaronabend 2026-08-27T00:00:00+00:00 ARI:0001135 Multiple sclerosis skos:exactMatch ncit:C3243 ncit semapv:ManualMappingCuration github:aaronabend 2026-08-27T00:00:00+00:00 diff --git a/ontologies/ari_t1d.owl b/ontologies/ari_t1d.owl index d7c58cb..dbb957a 100644 --- a/ontologies/ari_t1d.owl +++ b/ontologies/ari_t1d.owl @@ -599,7 +599,7 @@ 46635009 9744 C0011854 - MONDO:0005147 + 0005147 E10 1.0 ~0.5% global, ~1.6M US. ~500/100k globally. @@ -1565,7 +1565,7 @@ Latent autoimmune diabetes 9744 C2987933 - MONDO:0011027 + 0011027 E10 2026-06-12 | System | Initial subtype entry @@ -1842,6 +1842,7 @@ 2026-08-30T20:29:14+00:00 | user | Edited: mesh 2026-08-30T20:32:42+00:00 | user | Edited: doid 2026-08-30T20:37:56+00:00 | KrishnaTO | Cross-reference review: confirmed MONDO 0019139; confirmed NCI C197822; confirmed ICD10 D68.311; confirmed UMLS C1096116; no term in ORPHANET; no term in DOID + 12134 @@ -2073,7 +2074,6 @@ 13378 C0026691 M30.3 - 446.1 D009080 C34825 314381 @@ -2686,7 +2686,6 @@ The cause of Kawasaki's Disease is uncertain but is believed to be autoimmune. 10871 C0242383 H35.30 - 362.50 D008268 C84391 374028 @@ -2756,7 +2755,6 @@ However, based on the research available at this time, there is no evidence that 68225006 986 C0002171 - 704.01 L63 D000506 Alopecia areata is a type of hair loss that occurs when your immune system mistakenly attacks hair follicles, which is where hair growth begins. The damage to the follicle is usually not permanent. Experts do not know why the immune system attacks the follicles. @@ -2884,6 +2882,8 @@ However, based on the research available at this time, there is no evidence that 2026-07-02 16:36 | Krishna Udaiwal | Edited: age_range, clinical_subtypes, def_source, definition, demographic_bias, disease_category, doid, evidence_quality, icd10, incidence_rate, mesh, mondo, name, nci, obsolete, omop, prevalence_desc, prevalence_per_100k, prevalence_value, snomed, synonyms, umls 160 2026-07-22 15:42 | user | Edited: orphanet + Angiofollicular Lymph Node Hyperplasia, Unicentric - Affects a single lymph node. + Angiofollicular Lymph Node Hyperplasia, Multicentric - Involves multiple lymph nodes and systemic symptoms. @@ -3003,7 +3003,6 @@ However, based on the research available at this time, there is no evidence that 7147 C0038013 M45 - 720.0 D013167 C84564 437082 @@ -3166,6 +3165,7 @@ However, based on the research available at this time, there is no evidence that 1 Nervous System 2026-07-02 15:40 | Krishna Udaiwal | Edited: age_range, clinical_subtypes, def_source, definition, demographic_bias, disease_category, doid, evidence_quality, icd10, incidence_rate, mesh, mondo, name, nci, obsolete, omop, prevalence_desc, prevalence_per_100k, prevalence_value, snomed, synonyms, umls + Morvan syndrome @@ -3536,6 +3536,11 @@ The trigger for antisynthetase syndrome is unknown, but it may be associated wit 2024-09 ASY 2026-06-15 10:37 | Importer | Imported from ARI core reports + 2026-08-21 17:28 | linikujp | Cross-reference review: confirmed MONDO 0019344; confirmed ORPHANET 81 + 2026-08-21 17:35 | linikujp | Cross-reference review: confirmed MONDO 0019344; confirmed ORPHANET 81 + 2026-08-27 17:57 | aaronabend | Cross-reference review: confirmed SNOMED 445187004; confirmed OMOP 40482477; confirmed DOID 0080744; confirmed MONDO 0019344; confirmed ORPHANET 81 + 0019344 + 81 @@ -3637,7 +3642,6 @@ The trigger for antisynthetase syndrome is unknown, but it may be associated wit 306058006 12449 C0002874 - 284.9 D61.9 D000741 C2870 @@ -3663,8 +3667,32 @@ The trigger for antisynthetase syndrome is unknown, but it may be associated wit 2024-04 APA 2026-06-15 10:37 | Importer | Imported from ARI core reports + 2026-08-17 18:04 | KrishnaTO | Cross-reference review: confirmed SNOMED 306058006; confirmed OMOP 137829; confirmed DOID 12449; confirmed MONDO 0015909; confirmed NCI C2870; confirmed ICD10 D61.9; confirmed OMIM 609135; confirmed UMLS C0002874; confirmed MESH D000741; flagged ORPHANET 182040 + 2026-08-18 00:06 | KrishnaTO | Cross-reference review: confirmed SNOMED 306058006; confirmed OMOP 137829; confirmed DOID 12449; confirmed MONDO 0015909; confirmed NCI C2870; confirmed ICD10 D61.9; confirmed OMIM 609135; confirmed UMLS C0002874; confirmed MESH D000741; flagged ORPHANET 182040 + 2026-08-18 00:06 | KrishnaTO | Enrichment from confirmed cross-references: +6 synonym(s), +13 clinical subtype(s) 2026-08-20 16:32 | KrishnaTO | Cross-reference review: confirmed SNOMED 306058006; confirmed OMOP 137829; confirmed DOID 12449; confirmed MONDO 0015909; confirmed NCI C2870; confirmed ICD10 D61.9; confirmed OMIM 609135; confirmed UMLS C0002874; confirmed MESH D000741; flagged ORPHANET 182040 2026-08-30T20:37:56+00:00 | KrishnaTO | Cross-reference review: confirmed SNOMED 306058006; confirmed OMOP 137829; confirmed DOID 12449; confirmed MONDO 0015909; confirmed NCI C2870; confirmed ICD10 D61.9; confirmed OMIM 609135; confirmed UMLS C0002874; confirmed MESH D000741; flagged ORPHANET 182040 + 0015909 + 609135 + Aplastic Anemias + Aplastic anemia, unspecified + Aplastic Anaemia + Anemia, Aplastic + Aplastic Anaemias + Anaemia, Aplastic + idiopathic aplastic anemia - subtype of Aplastic anemia (MONDO:0012197) + Recurrent Aplastic Anemia - subtype of Aplastic anemia (NCIT:C153293) + acquired aplastic anemia - subtype of Aplastic anemia (MONDO:0015610) + congenital hypoplastic anemia - subtype of Aplastic anemia (DOID:1342) + Aplastic Anemia due to Infection - subtype of Aplastic anemia (NCIT:C35466) + Severe Aplastic Anemia - subtype of Aplastic anemia (NCIT:C61229) + inherited aplastic anemia - subtype of Aplastic anemia (MONDO:0001713) + myelophthisic anemia - subtype of Aplastic anemia (MONDO:0005868) + Very Severe Aplastic Anemia - subtype of Aplastic anemia (NCIT:C173788) + Non-Severe Aplastic Anemia - subtype of Aplastic anemia (NCIT:C173789) + Aplastic Anemia due to Radiation - subtype of Aplastic anemia (NCIT:C35465) + Drug/Toxin-Induced Aplastic Anemia - subtype of Aplastic anemia (NCIT:C70613) + Drug-Induced Aplastic Anemia - subtype of Aplastic anemia (NCIT:C35343) @@ -3880,7 +3908,6 @@ The trigger for antisynthetase syndrome is unknown, but it may be associated wit 232308006 9849 C0025281 - 386.0 H81.0 D008575 C185243 @@ -3987,6 +4014,8 @@ The trigger for antisynthetase syndrome is unknown, but it may be associated wit 2025-02 AE 2026-06-15 10:37 | Importer | Imported from ARI core reports + 2026-08-27 17:57 | aaronabend | Cross-reference review: confirmed OMOP 4318558; confirmed SNOMED 95643007; confirmed MONDO 0020640; no term in ICD10 + 0020640 @@ -4367,7 +4396,6 @@ When the NMDA receptor antibodies attack the NMDA receptors in the brain, certai 718716008 718 C0002880 - 283.0 D000744 C34378 441269, 36713763 @@ -4475,7 +4503,6 @@ When the NMDA receptor antibodies attack the NMDA receptors in the brain, certai 2048 C0241910 C1332355 - 571.42 D019693 C27778 200762, 36715923, 36717496, 36715924, 36687200 @@ -4667,7 +4694,6 @@ When the NMDA receptor antibodies attack the NMDA receptors in the brain, certai 6688 C1328840 D89.82 - 279.41 D056735 C37864 45765493 @@ -6256,6 +6282,7 @@ Cicatricial pemphigoid is usually not chronic, and most patients symptoms disapp 2026-06-15 10:37 | Importer | Imported from ARI core reports 2026-08-20 16:32 | KrishnaTO | Cross-reference review: confirmed ORPHANET 179 2026-08-30T20:37:56+00:00 | KrishnaTO | Cross-reference review: confirmed OMOP 4334133; confirmed ORPHANET 179 + 179 @@ -6278,7 +6305,6 @@ Cicatricial pemphigoid is usually not chronic, and most patients symptoms disapp 8506 C0030805 L12.0 - 694.5 D010391 C84389 4298692, 139899 @@ -6399,6 +6425,7 @@ Cicatricial pemphigoid is usually not chronic, and most patients symptoms disapp 2026-08-03 18:00 | KrishnaTO | Cross-reference review: confirmed SNOMED 838312001; confirmed OMOP 3654620 2026-08-03 18:15 | KrishnaTO | Cross-reference review: confirmed SNOMED 838312001; confirmed OMOP 3654620 2026-08-12 01:11 | KrishnaTO | Cross-reference review: confirmed SNOMED 838312001; confirmed OMOP 3654620 + 2026-08-15 22:37 | KrishnaTO | Cross-reference review: confirmed SNOMED 838312001; confirmed OMOP 3654620 @@ -6432,19 +6459,12 @@ The first reports of narcolepsy being an autoimmune disease came in 2013, but re 2025-02 CN 2026-06-15 10:37 | Importer | Imported from ARI core reports - 0016158 2026-08-03 00:06 | user | Edited: mondo - C196015 2026-08-03 00:07 | user | Edited: nci - G47.411 2026-08-03 00:08 | user | Edited: icd10 - 2073 - 2026-08-03 00:10 | user | Edited: orphanet - 161400 2026-08-03 00:10 | user | Edited: omim - C0751362 + 2026-08-03 00:10 | user | Edited: orphanet 2026-08-03 00:11 | user | Edited: umls - D009290 2026-08-03 00:12 | user | Edited: mesh 2026-08-03 00:19 | KrishnaTO | Cross-reference review: confirmed SNOMED 193042000; confirmed OMOP 437854; confirmed MONDO 0016158; confirmed ICD10 G47.411; confirmed ORPHANET 2073; confirmed UMLS C0751362; flagged SNOMED 735676003; flagged OMOP 42536721 2026-08-03 00:44 | KrishnaTO | Cross-reference review: confirmed SNOMED 193042000; confirmed OMOP 437854; confirmed MONDO 0016158; confirmed ICD10 G47.411; confirmed ORPHANET 2073; confirmed UMLS C0751362; flagged SNOMED 735676003; flagged OMOP 42536721 @@ -6457,10 +6477,57 @@ The first reports of narcolepsy being an autoimmune disease came in 2013, but re 2026-08-03 18:00 | KrishnaTO | Cross-reference review: confirmed SNOMED 193042000; confirmed OMOP 437854; confirmed MONDO 0016158; confirmed ICD10 G47.411; confirmed ORPHANET 2073; confirmed UMLS C0751362; flagged SNOMED 735676003; flagged OMOP 42536721 2026-08-03 18:15 | KrishnaTO | Cross-reference review: confirmed SNOMED 193042000; confirmed OMOP 437854; confirmed MONDO 0016158; confirmed ICD10 G47.411; confirmed ORPHANET 2073; confirmed UMLS C0751362; flagged SNOMED 735676003; flagged OMOP 42536721 2026-08-12 01:11 | KrishnaTO | Cross-reference review: confirmed SNOMED 193042000; confirmed OMOP 437854; confirmed MONDO 0016158; confirmed ICD10 G47.411; confirmed ORPHANET 2073; confirmed UMLS C0751362; flagged SNOMED 735676003; flagged OMOP 42536721 - 193042000 - 437854 + 2026-08-15 22:37 | KrishnaTO | Cross-reference review: confirmed SNOMED 193042000; confirmed OMOP 437854; confirmed MONDO 0016158; confirmed ICD10 G47.411; confirmed ORPHANET 2073; confirmed UMLS C0751362; flagged SNOMED 735676003; flagged OMOP 42536721 + 2026-08-15 22:38 | KrishnaTO | Enrichment from confirmed cross-references: +10 synonym(s), +3 clinical subtype(s) + 2026-08-16 00:31 | KrishnaTO | Cross-reference review: confirmed NCI C196015; confirmed MESH D009290; confirmed OMIM 161400; flagged DOID 8986 + 2026-08-16 00:31 | KrishnaTO | Enrichment from confirmed cross-references: +14 synonym(s), +1 clinical subtype(s) + 2026-08-16 20:13 | KrishnaTO | Cross-reference review: confirmed NCI C196015; confirmed OMIM 161400; confirmed MESH D009290; flagged DOID 8986; no term in DOID + 2026-08-16 21:56 | KrishnaTO | Cross-reference review: confirmed NCI C196015; confirmed OMIM 161400; confirmed MESH D009290; flagged DOID 8986; no term in DOID + 2026-08-17 18:04 | KrishnaTO | Cross-reference review: confirmed NCI C196015; confirmed OMIM 161400; confirmed MESH D009290; flagged DOID 8986; no term in DOID + 2026-08-18 00:06 | KrishnaTO | Cross-reference review: confirmed NCI C196015; confirmed OMIM 161400; confirmed MESH D009290; flagged DOID 8986; no term in DOID + 2026-08-18 00:06 | KrishnaTO | Enrichment from confirmed cross-references: +16 synonym(s), +2 clinical subtype(s) 2026-08-20 16:32 | KrishnaTO | Cross-reference review: confirmed NCI C196015; confirmed OMIM 161400; confirmed MESH D009290; flagged DOID 8986; no term in DOID 2026-08-30T20:37:56+00:00 | KrishnaTO | Cross-reference review: confirmed NCI C196015; confirmed OMIM 161400; confirmed MESH D009290; flagged DOID 8986; no term in DOID + 0016158 + C196015 + G47.411 + 2073 + 161400 + C0751362 + D009290 + 193042000 + 437854 + Narcolepsy, without cataplexy + narcolepsy with cataplexy + narcolepsy + Narcolepsy-cataplexy + narcolepsy-cataplexy syndrome + Hypocretin/orexin deficiency syndrome + paroxysmal sleep + Gelineau's syndrome + Gelineau disease + Gelineau syndrome + narcolepsy caused by mutation in HCRT + HCRT narcolepsy + Narcoleptic Syndrome + Syndrome, Gelineau's + Syndromes, Gelineau's + Syndrome, Narcoleptic + narcolepsy with or without cataplexy + Gelineaus Syndrome + Gelineau's Syndromes + Narcoleptic Syndromes + Syndrome, Gelineau + narcolepsy 1 + Sleep, Paroxysmal + Syndromes, Narcoleptic + narcolepsy 7 - subtype of Cataplexy and narcolepsy (MONDO:0013652) + narcolepsy 1 - subtype of Cataplexy and narcolepsy (MONDO:0008062) + narcolepsy 3 - subtype of Cataplexy and narcolepsy (MONDO:0012179) + hereditary narcolepsy - subtype of Cataplexy and narcolepsy (MONDO:0100554) + Gelineau Syndrome + Gelineau's Syndrome + narcolepsy-cataplexy syndrome - subtype of Cataplexy and narcolepsy (MONDO:0016158) @@ -6597,6 +6664,36 @@ CD is generally treated by eliminating gluten from the diet. Patients with an e 2026-08-12 01:11 | KrishnaTO | Cross-reference review: confirmed SNOMED 396331005; confirmed OMOP 194992; confirmed DOID 10608; confirmed MONDO 0005130; confirmed NCI C26714; confirmed ICD10 K90.0; confirmed ORPHANET 555; confirmed UMLS C0007570; confirmed MESH D002446; flagged SNOMED 91867008; flagged OMOP 4241413; flagged ICD10 579.0 396331005 194992 + Sprue, Nontropical + NON RARE IN EUROPE: Nontropical sprue + NON RARE IN EUROPE: Coeliac sprue + coeliac sprue + Enteropathy, Gluten-Sensitive + Sprue, Celiac + NON RARE IN EUROPE: Coeliac disease + NON RARE IN EUROPE: Gluten intolerance + Enteropathies, Gluten-Sensitive + idiopathic steatorrhea + Disease, Celiac + Sprue + gluten intolerance + NON RARE IN EUROPE: Celiac disease + NON RARE IN EUROPE: Celiac sprue + Gluten-Sensitive Enteropathies + NON RARE IN EUROPE: Idiopathic steatorrhea + Gluten Enteropathies + NON RARE IN EUROPE: Gluten-sensitive enteropathy + NON RARE IN EUROPE: Gluten-induced enteropathy + Enteropathies, Gluten + non tropical sprue + Gluten Enteropathy + Enteropathy, Gluten + Lane Hamilton syndrome - subtype of Celiac disease (MONDO:0800124) + Refractory Celiac Disease - subtype of Celiac disease (NCIT:C200033) + Collagenous Sprue - subtype of Celiac disease (NCIT:C45426) + Latent Celiac Disease - subtype of Celiac disease (NCIT:C45425) + 2026-08-15 22:37 | KrishnaTO | Cross-reference review: confirmed SNOMED 396331005; confirmed OMOP 194992; confirmed DOID 10608; confirmed MONDO 0005130; confirmed NCI C26714; confirmed ICD10 K90.0; confirmed ORPHANET 555; confirmed UMLS C0007570; confirmed MESH D002446; flagged SNOMED 91867008; flagged OMOP 4241413; flagged ICD10 579.0 + 2026-08-15 22:38 | KrishnaTO | Enrichment from confirmed cross-references: +24 synonym(s), +4 clinical subtype(s) @@ -6843,8 +6940,42 @@ The cause of this syndrome is unknown, however, researchers believe that it may 2026-08-03 18:00 | KrishnaTO | Cross-reference review: confirmed SNOMED 52702003; confirmed OMOP 432738; confirmed DOID 8544; confirmed MONDO 0005404; confirmed NCI C3037; confirmed ICD10 G93.32; confirmed ORPHANET 1983; confirmed UMLS C0015674; confirmed MESH D015673; flagged ICD10 780.71 2026-08-03 18:15 | KrishnaTO | Cross-reference review: confirmed SNOMED 52702003; confirmed OMOP 432738; confirmed DOID 8544; confirmed MONDO 0005404; confirmed NCI C3037; confirmed ICD10 G93.32; confirmed ORPHANET 1983; confirmed UMLS C0015674; confirmed MESH D015673; flagged ICD10 780.71 2026-08-12 01:11 | KrishnaTO | Cross-reference review: confirmed SNOMED 52702003; confirmed OMOP 432738; confirmed DOID 8544; confirmed MONDO 0005404; confirmed NCI C3037; confirmed ICD10 G93.32; confirmed ORPHANET 1983; confirmed UMLS C0015674; confirmed MESH D015673; flagged ICD10 780.71 + 2026-08-15 22:37 | KrishnaTO | Cross-reference review: confirmed SNOMED 52702003; confirmed OMOP 432738; confirmed DOID 8544; confirmed MONDO 0005404; confirmed NCI C3037; confirmed ICD10 G93.32; confirmed ORPHANET 1983; confirmed UMLS C0015674; confirmed MESH D015673; flagged ICD10 780.71 + 2026-08-15 22:38 | KrishnaTO | Enrichment from confirmed cross-references: +26 synonym(s) + 2026-08-16 20:13 | KrishnaTO | Cross-reference review: no term in OMIM + 2026-08-16 21:56 | KrishnaTO | Cross-reference review: no term in OMIM + 2026-08-17 18:04 | KrishnaTO | Cross-reference review: no term in OMIM + 2026-08-18 00:06 | KrishnaTO | Cross-reference review: no term in OMIM 2026-08-20 16:32 | KrishnaTO | Cross-reference review: no term in OMIM 2026-08-30T20:37:56+00:00 | KrishnaTO | Cross-reference review: no term in OMIM + myalgic encephalomeyelitis/chronic fatigue syndrome + Chronic Fatigue-Fibromyalgia Syndrome + Fatigue Syndrome, Postviral + Infectious Mononucleosis-Like Syndrome, Chronic + Fatigue Syndrome, Chronic + NON RARE IN EUROPE: Myalgic encephalomyelitis + Postviral Fatigue Syndromes + Chronic Fatigue Syndromes + Myalgic encephalitis + Fatigue-Fibromyalgia Syndrome, Chronic + Royal Free Disease + Chronic Fatigue and Immune Dysfunction Syndrome + Chronic Fatigue-Fibromyalgia Syndromes + Syndrome, Postviral Fatigue + chronic fatigue immune dysfunction syndrome + Postviral fatigue syndrome + Fatigue Disorder, Chronic + NON RARE IN EUROPE: Chronic fatigue syndrome + Fatigue Syndromes, Chronic + Fatigue-Fibromyalgia Syndromes, Chronic + Chronic Fatigue Disorder + Myalgic encephalomyelitis/chronic fatigue syndrome + CFS + Chronic Fatigue Disorders + NON RARE IN EUROPE: Chronic fatigue immune dysfunction syndrome + Encephalomyelitis, Myalgic + 0005404 + 1983 @@ -6926,9 +7057,7 @@ The cause of this syndrome is unknown, however, researchers believe that it may 2024-09 CIDP 2026-06-15 10:37 | Importer | Imported from ARI core reports - 0006702 2026-08-03 13:47 | user | Edited: mondo - 2932 2026-08-03 13:48 | user | Edited: orphanet 2026-08-03 14:03 | KrishnaTO | Cross-reference review: confirmed SNOMED 128209004; confirmed OMOP 381009; confirmed DOID 5213; confirmed MONDO 0006702; confirmed NCI C84636; confirmed ICD10 G61.81; confirmed ORPHANET 2932; confirmed UMLS C0393819; confirmed MESH D020277; flagged SNOMED 230564004; flagged OMOP 4048024; flagged ICD10 357.81 2026-08-03 14:09 | KrishnaTO | Cross-reference review: confirmed SNOMED 128209004; confirmed OMOP 381009; confirmed DOID 5213; confirmed MONDO 0006702; confirmed NCI C84636; confirmed ICD10 G61.81; confirmed ORPHANET 2932; confirmed UMLS C0393819; confirmed MESH D020277; flagged SNOMED 230564004; flagged OMOP 4048024; flagged ICD10 357.81 @@ -6939,10 +7068,34 @@ The cause of this syndrome is unknown, however, researchers believe that it may 2026-08-03 18:00 | KrishnaTO | Cross-reference review: confirmed SNOMED 128209004; confirmed OMOP 381009; confirmed DOID 5213; confirmed MONDO 0006702; confirmed NCI C84636; confirmed ICD10 G61.81; confirmed ORPHANET 2932; confirmed UMLS C0393819; confirmed MESH D020277; flagged SNOMED 230564004; flagged OMOP 4048024; flagged ICD10 357.81 2026-08-03 18:15 | KrishnaTO | Cross-reference review: confirmed SNOMED 128209004; confirmed OMOP 381009; confirmed DOID 5213; confirmed MONDO 0006702; confirmed NCI C84636; confirmed ICD10 G61.81; confirmed ORPHANET 2932; confirmed UMLS C0393819; confirmed MESH D020277; flagged SNOMED 230564004; flagged OMOP 4048024; flagged ICD10 357.81 2026-08-12 01:11 | KrishnaTO | Cross-reference review: confirmed SNOMED 128209004; confirmed OMOP 381009; confirmed DOID 5213; confirmed MONDO 0006702; confirmed NCI C84636; confirmed ICD10 G61.81; confirmed ORPHANET 2932; confirmed UMLS C0393819; confirmed MESH D020277; flagged SNOMED 230564004; flagged OMOP 4048024; flagged ICD10 357.81 - 128209004 - 381009 + 2026-08-15 22:37 | KrishnaTO | Cross-reference review: confirmed SNOMED 128209004; confirmed OMOP 381009; confirmed DOID 5213; confirmed MONDO 0006702; confirmed NCI C84636; confirmed ICD10 G61.81; confirmed ORPHANET 2932; confirmed UMLS C0393819; confirmed MESH D020277; flagged SNOMED 230564004; flagged OMOP 4048024; flagged ICD10 357.81 + 2026-08-15 22:38 | KrishnaTO | Enrichment from confirmed cross-references: +15 synonym(s), +1 clinical subtype(s) + 2026-08-16 20:13 | KrishnaTO | Cross-reference review: no term in OMIM + 2026-08-16 21:56 | KrishnaTO | Cross-reference review: no term in OMIM + 2026-08-17 18:04 | KrishnaTO | Cross-reference review: no term in OMIM + 2026-08-18 00:06 | KrishnaTO | Cross-reference review: no term in OMIM 2026-08-20 16:32 | KrishnaTO | Cross-reference review: no term in OMIM 2026-08-30T20:37:56+00:00 | KrishnaTO | Cross-reference review: no term in OMIM + 0006702 + 2932 + 128209004 + 381009 + Inflammatory Polyradiculoneuropathies, Chronic + Inflammatory Polyradiculopathy, Chronic + Polyradiculopathies, Chronic Inflammatory + Polyradiculoneuropathies, Chronic Inflammatory + Chronic Inflammatory Polyradiculoneuropathy + Chronic Inflammatory Polyradiculopathy + Polyneuropathy, Inflammatory Demyelinating, Chronic + Chronic Inflammatory Polyradiculopathies + Polyradiculoneuropathy, Chronic Inflammatory Demyelinating + Inflammatory Polyradiculopathies, Chronic + Chronic Inflammatory Polyradiculoneuropathies + CIDP + Polyradiculopathy, Chronic Inflammatory + Inflammatory Polyradiculoneuropathy, Chronic + Polyradiculoneuropathy, Chronic Inflammatory + Lewis-Sumner syndrome - subtype of Chronic inflammatory demyelinating polyradiculoneuropathy (MONDO:0018826) @@ -7044,17 +7197,12 @@ Currently, the cause of interstitial cystitis is unknown. There are two main the 2024-09 CIC 2026-06-15 10:37 | Importer | Imported from ARI core reports - 38731000087104 2026-07-12 21:44 | user | Edited: snomed - 1450471 2026-07-12 21:45 | user | Edited: omop - 0018301 - 2026-07-12 21:46 | user | Edited: mondo 2026-07-12 21:46 | user | Edited: icd10 - 37202 + 2026-07-12 21:46 | user | Edited: mondo 2026-07-12 21:47 | user | Edited: orphanet 2026-07-12 21:56 | KrishnaTO | Cross-reference review: confirmed DOID 1678; confirmed ICD10 N30.1; confirmed UMLS C0600040; confirmed MESH D018856 - C27189 2026-08-03 13:54 | user | Edited: nci 2026-08-03 14:03 | KrishnaTO | Cross-reference review: confirmed SNOMED 38731000087104; confirmed OMOP 1450471; confirmed DOID 1678; confirmed MONDO 0018301; confirmed NCI C27189; confirmed ICD10 N30.1; confirmed ORPHANET 37202; confirmed UMLS C0600040; confirmed MESH D018856 2026-08-03 14:09 | KrishnaTO | Cross-reference review: confirmed SNOMED 38731000087104; confirmed OMOP 1450471; confirmed DOID 1678; confirmed MONDO 0018301; confirmed NCI C27189; confirmed ICD10 N30.1; confirmed ORPHANET 37202; confirmed UMLS C0600040; confirmed MESH D018856 @@ -7065,8 +7213,29 @@ Currently, the cause of interstitial cystitis is unknown. There are two main the 2026-08-03 18:00 | KrishnaTO | Cross-reference review: confirmed SNOMED 38731000087104; confirmed OMOP 1450471; confirmed DOID 1678; confirmed MONDO 0018301; confirmed NCI C27189; confirmed ICD10 N30.1; confirmed ORPHANET 37202; confirmed UMLS C0600040; confirmed MESH D018856 2026-08-03 18:15 | KrishnaTO | Cross-reference review: confirmed SNOMED 38731000087104; confirmed OMOP 1450471; confirmed DOID 1678; confirmed MONDO 0018301; confirmed NCI C27189; confirmed ICD10 N30.1; confirmed ORPHANET 37202; confirmed UMLS C0600040; confirmed MESH D018856 2026-08-12 01:11 | KrishnaTO | Cross-reference review: confirmed SNOMED 38731000087104; confirmed OMOP 1450471; confirmed DOID 1678; confirmed MONDO 0018301; confirmed NCI C27189; confirmed ICD10 N30.1; confirmed ORPHANET 37202; confirmed UMLS C0600040; confirmed MESH D018856 + 2026-08-15 22:37 | KrishnaTO | Cross-reference review: confirmed SNOMED 38731000087104; confirmed OMOP 1450471; confirmed DOID 1678; confirmed MONDO 0018301; confirmed NCI C27189; confirmed ICD10 N30.1; confirmed ORPHANET 37202; confirmed UMLS C0600040; confirmed MESH D018856 + 2026-08-15 22:38 | KrishnaTO | Enrichment from confirmed cross-references: +10 synonym(s) + 2026-08-16 20:13 | KrishnaTO | Cross-reference review: no term in OMIM + 2026-08-16 21:56 | KrishnaTO | Cross-reference review: no term in OMIM + 2026-08-17 18:04 | KrishnaTO | Cross-reference review: no term in OMIM + 2026-08-18 00:06 | KrishnaTO | Cross-reference review: no term in OMIM 2026-08-20 16:32 | KrishnaTO | Cross-reference review: no term in OMIM 2026-08-30T20:37:56+00:00 | KrishnaTO | Cross-reference review: no term in OMIM + 38731000087104 + 1450471 + 0018301 + 37202 + C27189 + ulcerative cystitis + IC/BPS + IC/PBS + Interstitial Cystitides + interstitial cystitis + interstitial cystitis/painful bladder syndrome + Cystitides, Interstitial + interstitial cystitis/bladder pain syndrome + Cystitis, Interstitial + interstitial cystitis, chronic @@ -7189,14 +7358,10 @@ However, in some people, the Lyme disease triggers symptoms similar to rheumatoi 2024-09 CLD 2026-06-15 10:37 | Importer | Imported from ARI core reports - 0700280 2026-08-03 00:30 | user | Edited: mondo - C119039 2026-08-03 00:31 | user | Edited: nci 2026-08-03 00:37 | user | Edited: snomed - C3890422 2026-08-03 00:41 | user | Edited: umls - D000077342 2026-08-03 00:42 | user | Edited: mesh 2026-08-03 00:44 | KrishnaTO | Cross-reference review: flagged DOID 11729; flagged ICD10 088.81, A69.2; flagged SNOMED 1269516003 2026-08-03 14:03 | KrishnaTO | Cross-reference review: flagged DOID 11729; flagged ICD10 088.81, A69.2; flagged SNOMED 1269516003 @@ -7208,8 +7373,31 @@ However, in some people, the Lyme disease triggers symptoms similar to rheumatoi 2026-08-03 18:00 | KrishnaTO | Cross-reference review: flagged DOID 11729; flagged ICD10 088.81, A69.2; flagged SNOMED 1269516003 2026-08-03 18:15 | KrishnaTO | Cross-reference review: flagged DOID 11729; flagged ICD10 088.81, A69.2; flagged SNOMED 1269516003 2026-08-12 01:11 | KrishnaTO | Cross-reference review: flagged DOID 11729; flagged ICD10 088.81, A69.2; flagged SNOMED 1269516003 + 2026-08-15 22:37 | KrishnaTO | Cross-reference review: flagged DOID 11729; flagged ICD10 088.81, A69.2; flagged SNOMED 1269516003 + 2026-08-16 20:13 | KrishnaTO | Cross-reference review: confirmed MONDO 0700280; confirmed NCI C119039; confirmed UMLS C3890422; confirmed MESH D000077342; no term in ORPHANET; no term in DOID; no term in SNOMED; no term in ICD10; no term in OMIM + 2026-08-16 21:49 | user | Edited: omop + 2026-08-16 21:56 | KrishnaTO | Cross-reference review: confirmed MONDO 0700280; confirmed NCI C119039; confirmed UMLS C3890422; confirmed MESH D000077342; no term in ORPHANET; no term in DOID; no term in SNOMED; no term in ICD10; no term in OMIM + 2026-08-16 21:56 | KrishnaTO | Enrichment from confirmed cross-references: +9 synonym(s) + 2026-08-17 18:04 | KrishnaTO | Cross-reference review: confirmed MONDO 0700280; confirmed NCI C119039; confirmed UMLS C3890422; confirmed MESH D000077342; no term in ORPHANET; no term in DOID; no term in SNOMED; no term in ICD10; no term in OMIM + 2026-08-18 00:06 | KrishnaTO | Cross-reference review: confirmed MONDO 0700280; confirmed NCI C119039; confirmed UMLS C3890422; confirmed MESH D000077342; no term in ORPHANET; no term in DOID; no term in SNOMED; no term in ICD10; no term in OMIM + 2026-08-18 00:06 | KrishnaTO | Enrichment from confirmed cross-references: +9 synonym(s) 2026-08-20 16:32 | KrishnaTO | Cross-reference review: confirmed MONDO 0700280; confirmed NCI C119039; confirmed UMLS C3890422; confirmed MESH D000077342; no term in ORPHANET; no term in DOID; no term in SNOMED; no term in ICD10; no term in OMIM 2026-08-30T20:37:56+00:00 | KrishnaTO | Cross-reference review: confirmed MONDO 0700280; confirmed NCI C119039; confirmed UMLS C3890422; confirmed MESH D000077342; no term in ORPHANET; no term in DOID; no term in SNOMED; no term in ICD10; no term in OMIM + 0700280 + C119039 + C3890422 + D000077342 + Lyme Disease, Chronic + PTLDS + Syndrome, Post-Lyme Disease + post-Lyme disease syndrome + post-Lyme disease + disorder due to consequences of Lyme disease + Post-Lyme Disease Syndromes + Syndromes, Post-Lyme Disease + post-treatment Lyme disease syndrome + 19137845 + 37365579 @@ -7400,20 +7588,14 @@ Chronic non-bacterial osteomyelitis (CNO) is a rare auto-inflammatory bone disor 2024-09 CMO 2026-06-15 10:37 | Importer | Imported from ARI core reports - 1204420006 2026-07-12 21:50 | user | Edited: snomed - 37163124 - 2026-07-12 21:51 | user | Edited: omop - 0009813 2026-07-12 21:51 | user | Edited: mondo - C119042 2026-07-12 21:51 | user | Edited: nci - 324964 + 2026-07-12 21:51 | user | Edited: omop 2026-07-12 21:52 | user | Edited: orphanet + 2026-07-12 21:56 | KrishnaTO | Cross-reference review: confirmed DOID 0060645; confirmed ICD10 M86.3; confirmed MESH C535456 2026-07-12 21:56 | user | Edited: omim - C0410422 2026-07-12 21:56 | user | Edited: umls - 2026-07-12 21:56 | KrishnaTO | Cross-reference review: confirmed DOID 0060645; confirmed ICD10 M86.3; confirmed MESH C535456 2026-08-03 14:09 | KrishnaTO | Cross-reference review: confirmed SNOMED 1204420006; confirmed OMOP 37163124; confirmed DOID 0060645; confirmed MONDO 0009813; confirmed NCI C119042; confirmed ICD10 M86.3; confirmed ORPHANET 324964; confirmed UMLS C0410422; confirmed MESH C535456; flagged OMIM 609628 2026-08-03 14:23 | KrishnaTO | Cross-reference review: confirmed SNOMED 1204420006; confirmed OMOP 37163124; confirmed DOID 0060645; confirmed MONDO 0009813; confirmed NCI C119042; confirmed ICD10 M86.3; confirmed ORPHANET 324964; confirmed UMLS C0410422; confirmed MESH C535456; flagged OMIM 609628 2026-08-03 16:58 | KrishnaTO | Cross-reference review: confirmed SNOMED 1204420006; confirmed OMOP 37163124; confirmed DOID 0060645; confirmed MONDO 0009813; confirmed NCI C119042; confirmed ICD10 M86.3; confirmed ORPHANET 324964; confirmed UMLS C0410422; confirmed MESH C535456; flagged OMIM 609628 @@ -7422,8 +7604,29 @@ Chronic non-bacterial osteomyelitis (CNO) is a rare auto-inflammatory bone disor 2026-08-03 18:00 | KrishnaTO | Cross-reference review: confirmed SNOMED 1204420006; confirmed OMOP 37163124; confirmed DOID 0060645; confirmed MONDO 0009813; confirmed NCI C119042; confirmed ICD10 M86.3; confirmed ORPHANET 324964; confirmed UMLS C0410422; confirmed MESH C535456; flagged OMIM 609628 2026-08-03 18:15 | KrishnaTO | Cross-reference review: confirmed SNOMED 1204420006; confirmed OMOP 37163124; confirmed DOID 0060645; confirmed MONDO 0009813; confirmed NCI C119042; confirmed ICD10 M86.3; confirmed ORPHANET 324964; confirmed UMLS C0410422; confirmed MESH C535456; flagged OMIM 609628 2026-08-12 01:11 | KrishnaTO | Cross-reference review: confirmed SNOMED 1204420006; confirmed OMOP 37163124; confirmed DOID 0060645; confirmed MONDO 0009813; confirmed NCI C119042; confirmed ICD10 M86.3; confirmed ORPHANET 324964; confirmed UMLS C0410422; confirmed MESH C535456; flagged OMIM 609628 + 2026-08-15 22:37 | KrishnaTO | Cross-reference review: confirmed SNOMED 1204420006; confirmed OMOP 37163124; confirmed DOID 0060645; confirmed MONDO 0009813; confirmed NCI C119042; confirmed ICD10 M86.3; confirmed ORPHANET 324964; confirmed UMLS C0410422; confirmed MESH C535456; flagged OMIM 609628 + 2026-08-15 22:38 | KrishnaTO | Enrichment from confirmed cross-references: +7 synonym(s), +3 clinical subtype(s) + 2026-08-16 21:56 | KrishnaTO | Cross-reference review: no term in OMIM + 2026-08-17 18:04 | KrishnaTO | Cross-reference review: no term in OMIM + 2026-08-18 00:06 | KrishnaTO | Cross-reference review: no term in OMIM 2026-08-20 16:32 | KrishnaTO | Cross-reference review: no term in OMIM 2026-08-30T20:37:56+00:00 | KrishnaTO | Cross-reference review: no term in OMIM + 1204420006 + 37163124 + 0009813 + C119042 + 324964 + C0410422 + Chronic nonbacterial osteomyelitis/Chronic recurrent multifocal osteomyelitis + CNO/CRMO + non-bacterial osteomyelitis + chronic recurrent multifocal osteomyelitis + CRMO + NBO + chronic recurrent multifocal osteomyelitis (disease) + Majeed syndrome - subtype of Chronic multifocal osteomyelitis (MONDO:0012316) + sterile multifocal osteomyelitis with periostitis and pustulosis - subtype of Chronic multifocal osteomyelitis (MONDO:0013021) + chronic recurrent multifocal osteomyelitis 3 - subtype of Chronic multifocal osteomyelitis (MONDO:0958177) @@ -7638,16 +7841,11 @@ More study is needed. 2022-12 LCOV 2026-06-15 10:37 | Importer | Imported from ARI core reports - 0100233 2026-08-03 14:12 | user | Edited: mondo - C179263 - 2026-08-03 14:13 | user | Edited: nci - U09.9 2026-08-03 14:13 | user | Edited: icd10 - C5433293 - 2026-08-03 14:15 | user | Edited: umls - D000094024 + 2026-08-03 14:13 | user | Edited: nci 2026-08-03 14:15 | user | Edited: mesh + 2026-08-03 14:15 | user | Edited: umls 2026-08-03 14:23 | KrishnaTO | Cross-reference review: confirmed SNOMED 1119304009; confirmed OMOP 600589; confirmed DOID 0080848; confirmed MONDO 0100233; confirmed NCI C179263; confirmed UMLS C5433293; confirmed MESH D000094024 2026-08-03 16:58 | KrishnaTO | Cross-reference review: confirmed SNOMED 1119304009; confirmed OMOP 600589; confirmed DOID 0080848; confirmed MONDO 0100233; confirmed NCI C179263; confirmed UMLS C5433293; confirmed MESH D000094024 2026-08-03 17:14 | KrishnaTO | Cross-reference review: confirmed SNOMED 1119304009; confirmed OMOP 600589; confirmed DOID 0080848; confirmed MONDO 0100233; confirmed NCI C179263; confirmed UMLS C5433293; confirmed MESH D000094024 @@ -7655,8 +7853,38 @@ More study is needed. 2026-08-03 18:00 | KrishnaTO | Cross-reference review: confirmed SNOMED 1119304009; confirmed OMOP 600589; confirmed DOID 0080848; confirmed MONDO 0100233; confirmed NCI C179263; confirmed UMLS C5433293; confirmed MESH D000094024 2026-08-03 18:15 | KrishnaTO | Cross-reference review: confirmed SNOMED 1119304009; confirmed OMOP 600589; confirmed DOID 0080848; confirmed MONDO 0100233; confirmed NCI C179263; confirmed UMLS C5433293; confirmed MESH D000094024 2026-08-12 01:11 | KrishnaTO | Cross-reference review: confirmed SNOMED 1119304009; confirmed OMOP 600589; confirmed DOID 0080848; confirmed MONDO 0100233; confirmed NCI C179263; confirmed UMLS C5433293; confirmed MESH D000094024 + 2026-08-15 22:37 | KrishnaTO | Cross-reference review: confirmed SNOMED 1119304009; confirmed OMOP 600589; confirmed DOID 0080848; confirmed MONDO 0100233; confirmed NCI C179263; confirmed UMLS C5433293; confirmed MESH D000094024 + 2026-08-15 22:38 | KrishnaTO | Enrichment from confirmed cross-references: +15 synonym(s), +4 clinical subtype(s) + 2026-08-16 20:13 | KrishnaTO | Cross-reference review: no term in ORPHANET; no term in OMIM + 2026-08-16 21:56 | KrishnaTO | Cross-reference review: no term in ORPHANET; no term in OMIM + 2026-08-17 18:04 | KrishnaTO | Cross-reference review: no term in ORPHANET; no term in OMIM + 2026-08-18 00:06 | KrishnaTO | Cross-reference review: no term in ORPHANET; no term in OMIM 2026-08-20 16:32 | KrishnaTO | Cross-reference review: no term in ORPHANET; no term in OMIM 2026-08-30T20:37:56+00:00 | KrishnaTO | Cross-reference review: no term in ORPHANET; no term in OMIM + 0100233 + C179263 + U09.9 + C5433293 + D000094024 + Post-COVID Conditions + post-COVID syndrome + Post COVID-19 Syndrome + Post-Acute COVID-19 Syndrome + Long-Haul COVID + chronic COVID-19 + Long COVID-19 Syndrome + sequelae of COVID-19 + PASC + Post-Acute COVID-19 Sequelae + long haul COVID-19 + Postacute sequelae of SARS-CoV-2 infection (PASC) + long COVID-19 + PASC Post Acute Sequelae of COVID-19 + post-acute sequelae of SARS-CoV-2 infection + Neurovascular Disorder Associated with Post-Acute Sequelae of SARS-CoV-2 Infection - subtype of Chronic post-COVID-19 syndrome (NCIT:C191581) + Pulmonary Thromboembolic Disease Associated with Post-Acute Sequelae of SARS-CoV-2 Infection - subtype of Chronic post-COVID-19 syndrome (NCIT:C191611) + Deep Venous Thrombosis Associated with Post-Acute Sequelae of SARS-CoV-2 Infection - subtype of Chronic post-COVID-19 syndrome (NCIT:C191540) + Post-Acute Cardiovascular Sequelae of COVID-19 - subtype of Chronic post-COVID-19 syndrome (NCIT:C191431) @@ -7754,13 +7982,9 @@ More study is needed. 2024-09 COG 2026-06-15 10:37 | Importer | Imported from ARI core reports - 0060216 2026-08-03 14:17 | user | Edited: doid - 0015453 2026-08-03 14:18 | user | Edited: mondo - 1467 2026-08-03 14:19 | user | Edited: orphanet - D055952 2026-08-03 14:22 | user | Edited: mesh 2026-08-03 14:23 | KrishnaTO | Cross-reference review: confirmed SNOMED 405810005; confirmed OMOP 4233620; confirmed ICD10 H16.32; confirmed ORPHANET 1467; confirmed MESH D055952; flagged ICD10 370.52; flagged UMLS C0155089 2026-08-03 16:58 | KrishnaTO | Cross-reference review: confirmed SNOMED 405810005; confirmed OMOP 4233620; confirmed ICD10 H16.32; confirmed ORPHANET 1467; confirmed MESH D055952; flagged ICD10 370.52; flagged UMLS C0155089 @@ -7769,8 +7993,24 @@ More study is needed. 2026-08-03 18:00 | KrishnaTO | Cross-reference review: confirmed SNOMED 405810005; confirmed OMOP 4233620; confirmed ICD10 H16.32; confirmed ORPHANET 1467; confirmed MESH D055952; flagged ICD10 370.52; flagged UMLS C0155089 2026-08-03 18:15 | KrishnaTO | Cross-reference review: confirmed SNOMED 405810005; confirmed OMOP 4233620; confirmed ICD10 H16.32; confirmed ORPHANET 1467; confirmed MESH D055952; flagged ICD10 370.52; flagged UMLS C0155089 2026-08-12 01:11 | KrishnaTO | Cross-reference review: confirmed SNOMED 405810005; confirmed OMOP 4233620; confirmed ICD10 H16.32; confirmed ORPHANET 1467; confirmed MESH D055952; flagged ICD10 370.52; flagged UMLS C0155089 + 2026-08-15 22:37 | KrishnaTO | Cross-reference review: confirmed SNOMED 405810005; confirmed OMOP 4233620; confirmed ICD10 H16.32; confirmed ORPHANET 1467; confirmed MESH D055952; flagged ICD10 370.52; flagged UMLS C0155089 + 2026-08-15 22:38 | KrishnaTO | Enrichment from confirmed cross-references: +4 synonym(s) + 2026-08-16 20:13 | KrishnaTO | Cross-reference review: confirmed MONDO 0015453; no term in NCI; no term in OMIM + 2026-08-16 21:56 | KrishnaTO | Cross-reference review: confirmed UMLS C0271270; confirmed DOID 0060216; confirmed MONDO 0015453; no term in NCI; no term in OMIM + 2026-08-17 18:04 | KrishnaTO | Cross-reference review: confirmed DOID 0060216; confirmed MONDO 0015453; confirmed UMLS C0271270; no term in NCI; no term in OMIM + 2026-08-18 00:06 | KrishnaTO | Cross-reference review: confirmed DOID 0060216; confirmed MONDO 0015453; confirmed UMLS C0271270; no term in NCI; no term in OMIM + 2026-08-18 00:06 | KrishnaTO | Enrichment from confirmed cross-references: +2 synonym(s) 2026-08-20 16:32 | KrishnaTO | Cross-reference review: confirmed DOID 0060216; confirmed MONDO 0015453; confirmed UMLS C0271270; no term in NCI; no term in OMIM 2026-08-30T20:37:56+00:00 | KrishnaTO | Cross-reference review: confirmed DOID 0060216; confirmed MONDO 0015453; confirmed UMLS C0271270; no term in NCI; no term in OMIM + 0060216 + 0015453 + 1467 + D055952 + Cogan syndrome + Syndrome, Cogan's + diffuse interstitual keratitis + Syndrome, Cogan + C0271270 @@ -7922,28 +8162,66 @@ More study is needed. 2024-09 CAD 2026-06-15 10:37 | Importer | Imported from ARI core reports - 0018922 + 2026-08-03 16:55 | user | Edited: icd10 2026-08-03 16:55 | user | Edited: mondo - C208228 2026-08-03 16:55 | user | Edited: nci - D59.12 - 2026-08-03 16:55 | user | Edited: icd10 - 56425 2026-08-03 16:55 | user | Edited: orphanet - C0175816 2026-08-03 16:57 | user | Edited: umls - D000744 - 2026-08-03 16:58 | user | Edited: mesh 2026-08-03 16:58 | KrishnaTO | Cross-reference review: confirmed SNOMED 398937006; confirmed OMOP 4160887; confirmed MONDO 0018922; confirmed NCI C208228; confirmed ICD10 D59.12; confirmed ORPHANET 56425; confirmed UMLS C0175816; flagged SNOMED 127055007; flagged OMOP 4131128 + 2026-08-03 16:58 | user | Edited: mesh 2026-08-03 17:14 | KrishnaTO | Cross-reference review: confirmed SNOMED 398937006; confirmed OMOP 4160887; confirmed MONDO 0018922; confirmed NCI C208228; confirmed ICD10 D59.12; confirmed ORPHANET 56425; confirmed UMLS C0175816; flagged SNOMED 127055007; flagged OMOP 4131128 2026-08-03 17:22 | KrishnaTO | Cross-reference review: confirmed SNOMED 398937006; confirmed OMOP 4160887; confirmed MONDO 0018922; confirmed NCI C208228; confirmed ICD10 D59.12; confirmed ORPHANET 56425; confirmed UMLS C0175816; flagged SNOMED 127055007; flagged OMOP 4131128 2026-08-03 18:00 | KrishnaTO | Cross-reference review: confirmed SNOMED 398937006; confirmed OMOP 4160887; confirmed MONDO 0018922; confirmed NCI C208228; confirmed ICD10 D59.12; confirmed ORPHANET 56425; confirmed UMLS C0175816; flagged SNOMED 127055007; flagged OMOP 4131128 2026-08-03 18:15 | KrishnaTO | Cross-reference review: confirmed SNOMED 398937006; confirmed OMOP 4160887; confirmed MONDO 0018922; confirmed NCI C208228; confirmed ICD10 D59.12; confirmed ORPHANET 56425; confirmed UMLS C0175816; flagged SNOMED 127055007; flagged OMOP 4131128 2026-08-12 01:11 | KrishnaTO | Cross-reference review: confirmed SNOMED 398937006; confirmed OMOP 4160887; confirmed MONDO 0018922; confirmed NCI C208228; confirmed ICD10 D59.12; confirmed ORPHANET 56425; confirmed UMLS C0175816; flagged SNOMED 127055007; flagged OMOP 4131128 - 398937006 - 4160887 + 2026-08-15 22:37 | KrishnaTO | Cross-reference review: confirmed SNOMED 398937006; confirmed OMOP 4160887; confirmed MONDO 0018922; confirmed NCI C208228; confirmed ICD10 D59.12; confirmed ORPHANET 56425; confirmed UMLS C0175816; flagged SNOMED 127055007; flagged OMOP 4131128 + 2026-08-15 22:38 | KrishnaTO | Enrichment from confirmed cross-references: +7 synonym(s), +2 clinical subtype(s) + 2026-08-16 20:13 | KrishnaTO | Cross-reference review: confirmed MESH D000744; no term in OMIM + 2026-08-16 21:56 | KrishnaTO | Cross-reference review: confirmed MESH D000744; no term in DOID; no term in OMIM + 2026-08-16 21:56 | KrishnaTO | Enrichment from confirmed cross-references: +14 synonym(s), +6 clinical subtype(s) + 2026-08-17 18:04 | KrishnaTO | Cross-reference review: confirmed MESH D000744; no term in OMIM; no term in DOID + 2026-08-18 00:06 | KrishnaTO | Cross-reference review: confirmed MESH D000744; no term in OMIM; no term in DOID + 2026-08-18 00:06 | KrishnaTO | Enrichment from confirmed cross-references: +14 synonym(s), +7 clinical subtype(s) 2026-08-20 16:32 | KrishnaTO | Cross-reference review: confirmed MESH D000744; no term in OMIM; no term in DOID 2026-08-30T20:37:56+00:00 | KrishnaTO | Cross-reference review: confirmed MESH D000744; no term in OMIM; no term in DOID + 0018922 + C208228 + D59.12 + 56425 + C0175816 + D000744 + 398937006 + 4160887 + CAS + cAIHA + cAHA + cold agglutinin syndrome + cold AIHA + chronic cold agglutinin disease + autoimmune hemolytic anemia, cold type + Anaemia, Autoimmune Haemolytic + autoimmune hemolytic anemia + Anemia, Hemolytic, Acquired Autoimmune + Anemia, Autoimmune Hemolytic + autoimmune hemolytic anaemia + autoimmune haemolytic anemia + Anemia, Hemolytic, Autoimmune + Hemolytic Anemia, Autoimmune + Autoimmune Hemolytic Anemias + Haemolytic Anaemia, Autoimmune + AHA + Autoimmune haemolytic anaemia + AIHA + Autoimmune Haemolytic Anaemias + Primary Cold Agglutinin Disease - subtype of Cold agglutinin disease (NCIT:C199387) + paroxysmal cold hemoglobinuria - subtype of Cold agglutinin disease (MONDO:0019533) + mixed-type autoimmune hemolytic anemia - subtype of Cold agglutinin disease (MONDO:0019534) + Evans syndrome - subtype of Cold agglutinin disease (MONDO:0016030) + autoimmune hemolytic anemia, warm type - subtype of Cold agglutinin disease (MONDO:0019532) + giant cell hepatitis with autoimmune hemolytic anemia - subtype of Cold agglutinin disease (MONDO:1060166) + drug-induced autoimmune hemolytic anemia - subtype of Cold agglutinin disease (MONDO:0019535) + neonatal autoimmune hemolytic anemia - subtype of Cold agglutinin disease (MONDO:0018358) + autoimmune hemolytic anemia, cold type - subtype of Cold agglutinin disease (MONDO:0016450) @@ -8060,25 +8338,39 @@ More study is needed. Immune Deficiency 2.1 2026-06-15 10:37 | Importer | Imported from ARI core reports - 0081151 2026-08-03 17:03 | user | Edited: doid - 0013863 2026-08-03 17:04 | user | Edited: mondo - C176809 2026-08-03 17:06 | user | Edited: nci - 445018 2026-08-03 17:12 | user | Edited: orphanet - 614700 2026-08-03 17:13 | user | Edited: omim - C3553512 2026-08-03 17:13 | user | Edited: umls 2026-08-03 17:14 | KrishnaTO | Cross-reference review: confirmed SNOMED 1197477000; confirmed OMOP 37162777; confirmed DOID 0081151; confirmed MONDO 0013863; confirmed ORPHANET 445018; confirmed OMIM 614700; confirmed UMLS C3553512 2026-08-03 17:22 | KrishnaTO | Cross-reference review: confirmed SNOMED 1197477000; confirmed OMOP 37162777; confirmed DOID 0081151; confirmed MONDO 0013863; confirmed ORPHANET 445018; confirmed OMIM 614700; confirmed UMLS C3553512 2026-08-03 18:00 | KrishnaTO | Cross-reference review: confirmed SNOMED 1197477000; confirmed OMOP 37162777; confirmed DOID 0081151; confirmed MONDO 0013863; confirmed ORPHANET 445018; confirmed OMIM 614700; confirmed UMLS C3553512 2026-08-03 18:15 | KrishnaTO | Cross-reference review: confirmed SNOMED 1197477000; confirmed OMOP 37162777; confirmed DOID 0081151; confirmed MONDO 0013863; confirmed ORPHANET 445018; confirmed OMIM 614700; confirmed UMLS C3553512 2026-08-12 01:11 | KrishnaTO | Cross-reference review: confirmed SNOMED 1197477000; confirmed OMOP 37162777; confirmed DOID 0081151; confirmed MONDO 0013863; confirmed ORPHANET 445018; confirmed OMIM 614700; confirmed UMLS C3553512 + 2026-08-15 22:37 | KrishnaTO | Cross-reference review: confirmed SNOMED 1197477000; confirmed OMOP 37162777; confirmed DOID 0081151; confirmed MONDO 0013863; confirmed ORPHANET 445018; confirmed OMIM 614700; confirmed UMLS C3553512 + 2026-08-15 22:38 | KrishnaTO | Enrichment from confirmed cross-references: +7 synonym(s) + 2026-08-16 20:13 | KrishnaTO | Cross-reference review: confirmed NCI C176809; no term in ICD10; no term in MESH + 2026-08-16 21:56 | KrishnaTO | Cross-reference review: confirmed NCI C176809; no term in ICD10; no term in MESH + 2026-08-17 18:04 | KrishnaTO | Cross-reference review: confirmed NCI C176809; no term in ICD10; no term in MESH + 2026-08-18 00:06 | KrishnaTO | Cross-reference review: confirmed NCI C176809; no term in ICD10; no term in MESH + 2026-08-18 00:06 | KrishnaTO | Enrichment from confirmed cross-references: +2 synonym(s) 2026-08-20 16:32 | KrishnaTO | Cross-reference review: confirmed NCI C176809; no term in ICD10; no term in MESH 2026-08-30T20:37:56+00:00 | KrishnaTO | Cross-reference review: confirmed NCI C176809; no term in ICD10; no term in MESH + 0081151 + 0013863 + C176809 + 445018 + 614700 + C3553512 + Syndromic autoimmune enteropathy due to LPS responsive beige-like anchor protein + CID due to LRBA deficiency + Immunodeficiency, Common Variable, 8, with Autoimmunity + CVID8 + common variable immunodeficiency-8 (CVID8) with autoimmunity + Syndromic autoimmune enteropathy due to LRBA deficiency + common variable immunodeficiency 8 @@ -8130,20 +8422,49 @@ More study is needed. 2024-09 CPRS 2026-06-15 10:37 | Importer | Imported from ARI core reports - 0019369 2026-08-03 17:18 | user | Edited: mondo - 83452 2026-08-03 17:21 | user | Edited: orphanet - 604335 - 2026-08-03 17:22 | user | Edited: omim 2026-08-03 17:22 | KrishnaTO | Cross-reference review: confirmed SNOMED 128200000; confirmed OMOP 4134577; confirmed DOID 3223; confirmed MONDO 0019369; confirmed NCI C206547; confirmed ORPHANET 83452; confirmed UMLS C0458219; confirmed MESH D020918; flagged SNOMED 408751001, 734947007; flagged OMOP 42536233, 4256912 + 2026-08-03 17:22 | user | Edited: omim 2026-08-03 18:00 | KrishnaTO | Cross-reference review: confirmed SNOMED 128200000; confirmed OMOP 4134577; confirmed DOID 3223; confirmed MONDO 0019369; confirmed NCI C206547; confirmed ORPHANET 83452; confirmed UMLS C0458219; confirmed MESH D020918; flagged SNOMED 408751001, 734947007; flagged OMOP 42536233, 4256912 2026-08-03 18:15 | KrishnaTO | Cross-reference review: confirmed SNOMED 128200000; confirmed OMOP 4134577; confirmed DOID 3223; confirmed MONDO 0019369; confirmed NCI C206547; confirmed ORPHANET 83452; confirmed UMLS C0458219; confirmed MESH D020918; flagged SNOMED 408751001, 734947007; flagged OMOP 42536233, 4256912 2026-08-12 01:11 | KrishnaTO | Cross-reference review: confirmed SNOMED 128200000; confirmed OMOP 4134577; confirmed DOID 3223; confirmed MONDO 0019369; confirmed NCI C206547; confirmed ORPHANET 83452; confirmed UMLS C0458219; confirmed MESH D020918; flagged SNOMED 408751001, 734947007; flagged OMOP 42536233, 4256912 - 128200000 - 4134577 + 2026-08-15 22:37 | KrishnaTO | Cross-reference review: confirmed SNOMED 128200000; confirmed OMOP 4134577; confirmed DOID 3223; confirmed MONDO 0019369; confirmed NCI C206547; confirmed ORPHANET 83452; confirmed UMLS C0458219; confirmed MESH D020918; flagged SNOMED 408751001, 734947007; flagged OMOP 42536233, 4256912 + 2026-08-15 22:38 | KrishnaTO | Enrichment from confirmed cross-references: +9 synonym(s), +4 clinical subtype(s) + 2026-08-16 00:13 | KrishnaTO | Cross-reference review: confirmed OMIM 604335 + 2026-08-16 00:13 | KrishnaTO | Enrichment from confirmed cross-references: +5 synonym(s) + 2026-08-16 00:31 | KrishnaTO | Cross-reference review: confirmed OMIM 604335 + 2026-08-16 20:13 | KrishnaTO | Cross-reference review: confirmed ICD10 M89.0; confirmed OMIM 604335 + 2026-08-16 21:56 | KrishnaTO | Cross-reference review: confirmed OMIM 604335; confirmed ICD10 M89.0 + 2026-08-17 18:04 | KrishnaTO | Cross-reference review: confirmed OMIM 604335; confirmed ICD10 M89.0 + 2026-08-18 00:06 | KrishnaTO | Cross-reference review: confirmed OMIM 604335; confirmed ICD10 M89.0 + 2026-08-18 00:06 | KrishnaTO | Enrichment from confirmed cross-references: +1 synonym(s), +2 clinical subtype(s) 2026-08-20 16:32 | KrishnaTO | Cross-reference review: confirmed OMIM 604335; confirmed ICD10 M89.0 2026-08-30T20:37:56+00:00 | KrishnaTO | Cross-reference review: confirmed OMIM 604335; confirmed ICD10 M89.0 + 0019369 + 83452 + 604335 + 128200000 + 4134577 + Reflex sympathetic dystrophy + Pain Syndromes, Regional Complex + algoneurodystrophy + Complex regional pain syndromes + CRPS (Complex Regional Pain Syndromes) + Causalgia + CRPS + Sudeck's atrophy + Algodystrophy + Complex regional pain syndrome I + complex regional pain syndrome type 1 + reflex neurovascular dystrophy + CRPS I + reflex sympathetic dystrophy syndrome + complex regional pain syndrome type 2 - subtype of Complex regional pain syndrome (MONDO:0020572) + Complex Regional Pain Syndrome I - subtype of Complex regional pain syndrome (NCIT:C85042) + Complex Regional Pain Syndrome II - subtype of Complex regional pain syndrome (NCIT:C121572) + complex regional pain syndrome type 1 - subtype of Complex regional pain syndrome (MONDO:0011441) + M89.0 @@ -8253,6 +8574,14 @@ More study is needed. 2026-08-03 18:00 | KrishnaTO | Cross-reference review: confirmed DOID 0081242; flagged OMIM 616414 2026-08-03 18:15 | KrishnaTO | Cross-reference review: confirmed DOID 0081242; flagged OMIM 616414 2026-08-12 01:11 | KrishnaTO | Cross-reference review: confirmed DOID 0081242; flagged OMIM 616414 + autoimmune interstitial lung, joint, and kidney disease + Autoimmune interstitial lung disease-arthritis syndrome + systemic autoinflammation and autoimmunity with immune dysregulation 1 + autoinflammation and autoimmunity, Systemic with immune dysregulation + autoinflammation and autoimmunity with immune dysregulation 2 - subtype of COPA syndrome (MONDO:0700392) + autoinflammation and autoimmunity with immune dysregulation 1 - subtype of COPA syndrome (MONDO:0700391) + 2026-08-15 22:37 | KrishnaTO | Cross-reference review: confirmed DOID 0081242; flagged OMIM 616414 + 2026-08-15 22:38 | KrishnaTO | Enrichment from confirmed cross-references: +4 synonym(s), +2 clinical subtype(s) @@ -8309,13 +8638,56 @@ Both UC and CD are caused by an autoimmune response that reflects the involvemen 2023-01 CRD 2026-06-15 10:37 | Importer | Imported from ARI core reports - K50 2026-08-12 01:00 | user | Edited: icd10 - C2965 2026-08-12 01:01 | user | Edited: nci 2026-08-12 01:11 | KrishnaTO | Cross-reference review: confirmed SNOMED 34000006; confirmed MONDO 0005011; confirmed DOID 8778; flagged ICD10 555.1 + 2026-08-15 22:37 | KrishnaTO | Cross-reference review: confirmed SNOMED 34000006; confirmed MONDO 0005011; confirmed DOID 8778; flagged ICD10 555.1 + 2026-08-15 22:38 | KrishnaTO | Enrichment from confirmed cross-references: +14 synonym(s), +6 clinical subtype(s) + 2026-08-16 00:13 | KrishnaTO | Cross-reference review: confirmed OMOP 201606; confirmed NCI C2965; confirmed ICD10 K50; confirmed ORPHANET 206; confirmed MESH D003424 + 2026-08-16 00:13 | KrishnaTO | Enrichment from confirmed cross-references: +3 synonym(s), +3 clinical subtype(s) + 2026-08-16 00:31 | KrishnaTO | Cross-reference review: confirmed ICD10 K50; confirmed NCI C2965; confirmed OMOP 201606; confirmed ORPHANET 206; confirmed MESH D003424 + 2026-08-16 20:07 | user | Edited: omim + 2026-08-16 20:08 | user | Edited: umls + 2026-08-16 20:13 | KrishnaTO | Cross-reference review: confirmed ICD10 K50; confirmed NCI C2965; confirmed OMOP 201606; confirmed ORPHANET 206; confirmed MESH D003424 + 2026-08-16 21:56 | KrishnaTO | Cross-reference review: confirmed ICD10 K50; confirmed NCI C2965; confirmed OMOP 201606; confirmed ORPHANET 206; confirmed MESH D003424 + 2026-08-17 18:04 | KrishnaTO | Cross-reference review: confirmed ICD10 K50; confirmed NCI C2965; confirmed OMOP 201606; confirmed ORPHANET 206; confirmed MESH D003424 + 2026-08-18 00:06 | KrishnaTO | Cross-reference review: confirmed ICD10 K50; confirmed NCI C2965; confirmed OMOP 201606; confirmed ORPHANET 206; confirmed MESH D003424 + 2026-08-18 00:06 | KrishnaTO | Enrichment from confirmed cross-references: +9 synonym(s), +7 clinical subtype(s) 2026-08-20 16:32 | KrishnaTO | Cross-reference review: confirmed ICD10 K50; confirmed NCI C2965; confirmed OMOP 201606; confirmed ORPHANET 206; confirmed MESH D003424 2026-08-30T20:37:56+00:00 | KrishnaTO | Cross-reference review: confirmed ICD10 K50; confirmed NCI C2965; confirmed OMOP 201606; confirmed ORPHANET 206; confirmed MESH D003424 + K50 + C2965 + Crohn disease-associated growth failure + Granulomatous Colitis + inflammatory bowel disease caused by mutation in NOD2 + inflammatory bowel disease 1, Crohn disease + pediatric Crohn's disease + inflammatory bowel disease 1 + regional enteritis + inflammatory bowel disease (Crohn disease) 1 + NOD2 inflammatory bowel disease + Crohn's disease of colon + Crohn's disease of large bowel + inflammatory bowel disease type 1 + paediatric Crohn's disease + Crohn disease + NON RARE IN EUROPE: Crohn disease + Crohn's Enteritis + Crohns Disease + perianal Crohn disease - subtype of Crohn's disease (MONDO:0005537) + Crohn disease of the esophagus - subtype of Crohn's disease (MONDO:0022901) + oral Crohn disease - subtype of Crohn's disease (MONDO:0005535) + small bowel Crohn disease - subtype of Crohn's disease (MONDO:0005539) + ileitis - subtype of Crohn's disease (DOID:0060189) + jejunoileitis - subtype of Crohn's disease (DOID:0060188) + Crohn Disease of Rectum - subtype of Crohn's disease (NCIT:C219892) + Crohn Disease of Small Intestine - subtype of Crohn's disease (NCIT:C35210) + Crohn Colitis - subtype of Crohn's disease (NCIT:C35211) + C0010346 + 0005011 + 206 + 266600 + Inflammatory Bowel Disease 1 @@ -8410,7 +8782,6 @@ Both UC and CD are caused by an autoimmune response that reflects the involvemen 719218000 2797 C0085786 - 516.33 J84.114 D000080203 C35806 @@ -8434,8 +8805,46 @@ Both UC and CD are caused by an autoimmune response that reflects the involvemen 2024-09 COP 2026-06-15 10:37 | Importer | Imported from ARI core reports + 2026-08-16 00:13 | KrishnaTO | Cross-reference review: confirmed SNOMED 719218000; confirmed OMOP 36714118; confirmed DOID 2797; confirmed MONDO 0015264; confirmed ORPHANET 1302; flagged ICD10 516.33; no term in OMIM + 2026-08-16 00:13 | KrishnaTO | Enrichment from confirmed cross-references: +10 synonym(s), +10 clinical subtype(s) + 2026-08-16 00:31 | KrishnaTO | Cross-reference review: confirmed SNOMED 719218000; confirmed OMOP 36714118; confirmed DOID 2797; confirmed MONDO 0015264; confirmed ORPHANET 1302; flagged ICD10 516.33; no term in OMIM + 2026-08-16 20:09 | user | Edited: nci + 2026-08-16 20:10 | user | Edited: icd10 + 2026-08-16 20:11 | user | Edited: mesh + 2026-08-16 20:11 | user | Edited: umls + 2026-08-16 20:13 | KrishnaTO | Cross-reference review: confirmed SNOMED 719218000; confirmed OMOP 36714118; confirmed DOID 2797; confirmed MONDO 0015264; confirmed ORPHANET 1302; no term in OMIM + 2026-08-16 21:56 | KrishnaTO | Cross-reference review: confirmed SNOMED 719218000; confirmed OMOP 36714118; confirmed DOID 2797; confirmed MONDO 0015264; confirmed ORPHANET 1302; no term in OMIM + 2026-08-17 18:04 | KrishnaTO | Cross-reference review: confirmed SNOMED 719218000; confirmed OMOP 36714118; confirmed DOID 2797; confirmed MONDO 0015264; confirmed ORPHANET 1302; no term in OMIM + 2026-08-18 00:06 | KrishnaTO | Cross-reference review: confirmed SNOMED 719218000; confirmed OMOP 36714118; confirmed DOID 2797; confirmed MONDO 0015264; confirmed ORPHANET 1302; no term in OMIM + 2026-08-18 00:06 | KrishnaTO | Enrichment from confirmed cross-references: +10 synonym(s), +10 clinical subtype(s) 2026-08-20 16:32 | KrishnaTO | Cross-reference review: confirmed SNOMED 719218000; confirmed OMOP 36714118; confirmed DOID 2797; confirmed MONDO 0015264; confirmed ORPHANET 1302; no term in OMIM 2026-08-30T20:37:56+00:00 | KrishnaTO | Cross-reference review: confirmed SNOMED 719218000; confirmed OMOP 36714118; confirmed DOID 2797; confirmed MONDO 0015264; confirmed ORPHANET 1302; no term in OMIM + organising pneumonia + cryptogenic organizing pneumonitis + Idiopathic fibrosing alveolitis + idiopathic interstitial pneumonitis + noninfectious pneumonia + COP + Diffuse idiopathic pulmonary fibrosis + Organizing Pneumonia + bronchiolitis obliterans organizing pneumonia + BOOP + acute interstitial pneumonia - subtype of Cryptogenic organizing pneumonia (DOID:2800) + desquamative interstitial pneumonia - subtype of Cryptogenic organizing pneumonia (DOID:0050158) + idiopathic pleuroparenchymal fibroelastosis - subtype of Cryptogenic organizing pneumonia (MONDO:0044633) + non-specific interstitial pneumonia - subtype of Cryptogenic organizing pneumonia (MONDO:0019622) + idiopathic pulmonary fibrosis - subtype of Cryptogenic organizing pneumonia (MONDO:0800504) + follicular bronchiolits - subtype of Cryptogenic organizing pneumonia (MONDO:0800114) + nonspecific interstitial pneumonia - subtype of Cryptogenic organizing pneumonia (DOID:2801) + combined pulmonary fibrosis-emphysema syndrome - subtype of Cryptogenic organizing pneumonia (MONDO:0017591) + respiratory bronchiolitis-interstitial lung disease syndrome - subtype of Cryptogenic organizing pneumonia (MONDO:0019204) + lymphoid interstitial pneumonia - subtype of Cryptogenic organizing pneumonia (DOID:0050159) + J84.116 + D018549 + C62586 + C0242770 + 0015264 + 1302 @@ -8519,10 +8928,35 @@ Both UC and CD are caused by an autoimmune response that reflects the involvemen 2024-09 CLE 2026-06-15 10:37 | Importer | Imported from ARI core reports - 7119001 - 4324123 + 2026-08-16 00:11 | user | Edited: orphanet + 2026-08-16 00:13 | KrishnaTO | Cross-reference review: confirmed DOID 0050169; confirmed MONDO 0005282; confirmed NCI C26819; confirmed UMLS C0024137; confirmed MESH D008178; no term in OMIM + 2026-08-16 00:13 | KrishnaTO | Enrichment from confirmed cross-references: +1 synonym(s), +8 clinical subtype(s) + 2026-08-16 00:31 | KrishnaTO | Cross-reference review: confirmed DOID 0050169; confirmed MONDO 0005282; confirmed NCI C26819; confirmed UMLS C0024137; confirmed MESH D008178; no term in OMIM + 2026-08-16 20:13 | KrishnaTO | Cross-reference review: confirmed DOID 0050169; confirmed MONDO 0005282; confirmed NCI C26819; confirmed UMLS C0024137; confirmed MESH D008178; no term in OMIM + 2026-08-16 20:13 | user | Edited: icd10 + 2026-08-16 21:56 | KrishnaTO | Cross-reference review: confirmed DOID 0050169; confirmed MONDO 0005282; confirmed NCI C26819; confirmed UMLS C0024137; confirmed MESH D008178; no term in OMIM + 2026-08-17 18:04 | KrishnaTO | Cross-reference review: confirmed DOID 0050169; confirmed MONDO 0005282; confirmed NCI C26819; confirmed UMLS C0024137; confirmed MESH D008178; no term in OMIM + 2026-08-18 00:06 | KrishnaTO | Cross-reference review: confirmed DOID 0050169; confirmed MONDO 0005282; confirmed NCI C26819; confirmed UMLS C0024137; confirmed MESH D008178; no term in OMIM + 2026-08-18 00:06 | KrishnaTO | Enrichment from confirmed cross-references: +1 synonym(s), +8 clinical subtype(s) 2026-08-20 16:32 | KrishnaTO | Cross-reference review: confirmed DOID 0050169; confirmed MONDO 0005282; confirmed NCI C26819; confirmed UMLS C0024137; confirmed MESH D008178; no term in OMIM 2026-08-30T20:37:56+00:00 | KrishnaTO | Cross-reference review: confirmed DOID 0050169; confirmed MONDO 0005282; confirmed NCI C26819; confirmed UMLS C0024137; confirmed MESH D008178; no term in OMIM + 7119001 + 4324123 + Lupus Erythematosus, Cutaneous + Systemic Lupus Erythematosus Rash - subtype of Cutaneous lupus erythematosus (NCIT:C27171) + subacute cutaneous lupus erythematosus - subtype of Cutaneous lupus erythematosus (MONDO:0015573) + Chilblain lupus - subtype of Cutaneous lupus erythematosus (DOID:0060386) + Lupus Erythematosus Tumidus - subtype of Cutaneous lupus erythematosus (NCIT:C117112) + bullous systemic lupus erythematosus - subtype of Cutaneous lupus erythematosus (MONDO:0044113) + chronic cutaneous lupus erythematosus - subtype of Cutaneous lupus erythematosus (MONDO:0015574) + Rowell syndrome - subtype of Cutaneous lupus erythematosus (MONDO:0041186) + Drug Induced Cutaneous Lupus Erythematosus - subtype of Cutaneous lupus erythematosus (NCIT:C112203) + L93.0 + D008178 + C26819 + C0024137 + 0005282 + 535 @@ -8677,7 +9111,6 @@ When mastocytosis is not limited to the skin, it is called systemic mastocytosis 8505 C0011608 L13.0 - 694.0 D003874 C26742 140487 @@ -8798,7 +9231,6 @@ When mastocytosis is not limited to the skin, it is called systemic mastocytosis 10223 C0011633 M33 - 710.3 D003882 C26744 80182, 4005037 @@ -8894,7 +9326,6 @@ When mastocytosis is not limited to the skin, it is called systemic mastocytosis 0050214 C0022972 G70.80 - 358.3 D015624 C3155 4237155 @@ -9042,7 +9473,6 @@ When mastocytosis is not limited to the skin, it is called systemic mastocytosis 129103003 289 C0014175 - 617 N80 D004715 C3014 @@ -9329,7 +9759,6 @@ When mastocytosis is not limited to the skin, it is called systemic mastocytosis 13922 C0341106 K20.0 - 530.13 D057765 C27105 27918 @@ -9451,7 +9880,6 @@ When mastocytosis is not limited to the skin, it is called systemic mastocytosis 1826 C0014544 G40.909 - 345.9 D004827 C3020 380378 @@ -9760,6 +10188,11 @@ When mastocytosis is not limited to the skin, it is called systemic mastocytosis 2024-09 EMC 2026-06-15 10:37 | Importer | Imported from ARI core reports + 2026-08-20 17:04 | linikujp | Cross-reference review: confirmed MONDO 0007407; confirmed ORPHANET 91138 + 2026-08-21 17:28 | linikujp | Cross-reference review: confirmed MONDO 0007407; confirmed ORPHANET 91138 + 2026-08-21 17:35 | linikujp | Cross-reference review: confirmed MONDO 0007407; confirmed ORPHANET 91138 + 0007407 + 91138 @@ -10739,6 +11172,9 @@ ASA is not a concern except for people trying to conceive. 1% of all cases of hemophilia B; NR 2.1 2026-06-15 10:37 | Importer | Imported from ARI core reports + 2026-08-21 17:35 | linikujp | Cross-reference review: confirmed MONDO 0850054; confirmed ORPHANET 617930 + 0850054 + 617930 @@ -10904,7 +11340,6 @@ ASA is not a concern except for people trying to conceive. 60555002 9809 C0151436 - 446.2 M31.0 D018366 C35119 @@ -10987,6 +11422,8 @@ ASA is not a concern except for people trying to conceive. 2026-07-24 20:33 | AnjaliRH | Cross-reference review: confirmed SNOMED 722119002; confirmed OMOP 36716199; confirmed MONDO 0013860; confirmed NCI C123060; confirmed ORPHANET 97560; confirmed MESH D015433; flagged OMIM 614692 2026-07-24 20:38 | AnjaliRH | Cross-reference review: confirmed SNOMED 722119002; confirmed OMOP 36716199; confirmed MONDO 0013860; confirmed NCI C123060; confirmed ORPHANET 97560; confirmed MESH D015433; flagged OMIM 614692 2026-07-24 20:45 | AnjaliRH | Cross-reference review: confirmed SNOMED 722119002; confirmed OMOP 36716199; confirmed MONDO 0013860; confirmed NCI C123060; confirmed ORPHANET 97560; confirmed MESH D015433; flagged OMIM 614692 + 2026-08-10 14:32 | user | Edited: umls + C0086445 @@ -11005,7 +11442,6 @@ ASA is not a concern except for people trying to conceive. 0050156 C1800706 J84.112 - 516.31 D054990 C35716 45763750 @@ -11036,6 +11472,7 @@ ASA is not a concern except for people trying to conceive. 2026-07-24 20:37 | user | Edited: mondo 2026-07-24 20:38 | AnjaliRH | Cross-reference review: confirmed MESH D054990; confirmed ORPHANET 2032; confirmed ICD10 J84.112; confirmed NCI C35716; confirmed MONDO 0800504; confirmed DOID 0050156; confirmed OMOP 45763750; confirmed SNOMED 700250006; flagged OMIM 178500 2026-07-24 20:45 | AnjaliRH | Cross-reference review: confirmed MESH D054990; confirmed ORPHANET 2032; confirmed ICD10 J84.112; confirmed NCI C35716; confirmed MONDO 0800504; confirmed DOID 0050156; confirmed OMOP 45763750; confirmed SNOMED 700250006; flagged OMIM 178500 + 2026-08-10 14:32 | AnjaliRH | Cross-reference review: confirmed UMLS C1800706 @@ -11126,6 +11563,7 @@ ASA is not a concern except for people trying to conceive. 2026-07-24 20:43 | user | Edited: orphanet 2026-07-24 20:45 | user | Edited: mesh 2026-07-24 20:45 | AnjaliRH | Cross-reference review: confirmed SNOMED 236407003; confirmed OMOP 4128061; confirmed DOID 2986; confirmed MONDO 0005342; confirmed NCI C34643; confirmed ORPHANET 34145; confirmed MESH D005922 + 2026-08-10 14:32 | AnjaliRH | Cross-reference review: confirmed UMLS C0017661 @@ -11196,9 +11634,12 @@ ASA is not a concern except for people trying to conceive. ARI:0001105 2.1 2026-06-15 10:37 | Importer | Imported from ARI core reports + 2026-08-03 18:01 | AnjaliRH | Cross-reference review: confirmed MESH null + 2026-08-03 18:08 | AnjaliRH | Cross-reference review: confirmed MESH null 2026-08-03 18:43 | AnjaliRH | Cross-reference review: confirmed MESH null 2026-08-07 20:38 | AnjaliRH | Cross-reference review: confirmed MESH null 2026-08-07 20:42 | AnjaliRH | Cross-reference review: confirmed MESH null + 2026-08-10 14:32 | AnjaliRH | Cross-reference review: confirmed MESH null @@ -11211,21 +11652,32 @@ ASA is not a concern except for people trying to conceive. Immune Deficiency 2.1 2026-06-15 10:37 | Importer | Imported from ARI core reports + 2026-08-03 17:36 | user | Edited: orphanet + 2026-08-03 17:37 | user | Edited: nci + 2026-08-03 17:38 | user | Edited: mondo + 2026-08-03 17:40 | AnjaliRH | Cross-reference review: confirmed OMOP 28660; confirmed DOID 0090110; confirmed MESH C580192; confirmed OMIM 304790; confirmed ORPHANET 37042; confirmed NCI C131009; confirmed MONDO 0010580; flagged SNOMED 237618001; flagged ICD10 E31.0 + 2026-08-03 17:44 | user | Edited: mesh + 2026-08-03 17:44 | user | Edited: omim + 2026-08-03 17:44 | user | Edited: umls + 2026-08-03 18:01 | AnjaliRH | Cross-reference review: confirmed OMOP 28660; confirmed DOID 0090110; confirmed ORPHANET 37042; confirmed NCI C131009; confirmed MONDO 0010580; confirmed OMIM 304790; confirmed UMLS C0342288; flagged SNOMED 237618001; flagged ICD10 E31.0 + 2026-08-03 18:08 | AnjaliRH | Cross-reference review: confirmed OMOP 28660; confirmed DOID 0090110; confirmed ORPHANET 37042; confirmed NCI C131009; confirmed MONDO 0010580; confirmed OMIM 304790; confirmed UMLS C0342288; flagged SNOMED 237618001; flagged ICD10 E31.0 2026-08-03 18:43 | AnjaliRH | Cross-reference review: confirmed OMOP 28660; confirmed DOID 0090110; confirmed ORPHANET 37042; confirmed NCI C131009; confirmed MONDO 0010580; confirmed OMIM 304790; confirmed UMLS C0342288; flagged SNOMED 237618001; flagged ICD10 E31.0 - 0010580 2026-08-07 20:26 | user | Edited: mondo - C131009 2026-08-07 20:26 | user | Edited: nci - 37042 2026-08-07 20:26 | user | Edited: orphanet - 304790 2026-08-07 20:27 | user | Edited: omim - C0342288 2026-08-07 20:27 | user | Edited: umls - C580192 2026-08-07 20:28 | user | Edited: mesh 2026-08-07 20:38 | AnjaliRH | Cross-reference review: confirmed OMOP 28660; confirmed DOID 0090110; flagged SNOMED 237618001; flagged ICD10 E31.0 2026-08-07 20:42 | AnjaliRH | Cross-reference review: confirmed OMOP 28660; confirmed DOID 0090110; flagged SNOMED 237618001; flagged ICD10 E31.0 + 2026-08-10 14:32 | AnjaliRH | Cross-reference review: confirmed OMOP 28660; confirmed DOID 0090110; flagged SNOMED 237618001; flagged ICD10 E31.0 + 0010580 + C131009 + 37042 + 304790 + C0342288 + C580192 + 0090110 @@ -11282,19 +11734,25 @@ Note that thrombotic thrombocytopenic purpura, TTP, is a ***genetic*** disease t 2024-09 IT 2026-06-15 10:37 | Importer | Imported from ARI core reports + 2026-08-03 18:01 | AnjaliRH | Cross-reference review: flagged DOID 8924 + 2026-08-03 18:08 | AnjaliRH | Cross-reference review: flagged DOID 8924 + 2026-08-03 18:08 | user | Edited: mondo 2026-08-03 18:43 | AnjaliRH | Cross-reference review: flagged DOID 8924 - 0002048 2026-08-07 20:30 | user | Edited: mondo 2026-08-07 20:30 | user | Edited: nci - 3002 - 2026-08-07 20:32 | user | Edited: orphanet - 188030 2026-08-07 20:32 | user | Edited: omim + 2026-08-07 20:32 | user | Edited: orphanet 2026-08-07 20:34 | user | Edited: mesh 2026-08-07 20:38 | AnjaliRH | Cross-reference review: flagged DOID 8924; flagged ICD10 D69.3, 287.31 2026-08-07 20:42 | AnjaliRH | Cross-reference review: flagged DOID 8924; flagged ICD10 D69.3, 287.31 + 2026-08-10 14:32 | AnjaliRH | Cross-reference review: confirmed UMLS C0242584; flagged DOID 8924; flagged ICD10 D69.3, 287.31 + 2026-08-10 14:32 | AnjaliRH | Cross-reference review: confirmed UMLS C0398650; flagged DOID 8924; flagged ICD10 D69.3, 287.31 + 0002048 + 3002 + 188030 2897005 4103532 + C0242584 @@ -11408,7 +11866,6 @@ Note that thrombotic thrombocytopenic purpura, TTP, is a ***genetic*** disease t 191306005 11123 C0034152 - 287.0 D69.0 D011695 C34963 @@ -11437,14 +11894,18 @@ This condition is usually temporary (4-6 weeks) with a full recovery for most pa 2024-09 IAV 2026-06-15 10:37 | Importer | Imported from ARI core reports + 2026-08-03 18:01 | AnjaliRH | Cross-reference review: confirmed SNOMED 191306005; confirmed OMOP 4101602; confirmed DOID 11123 + 2026-08-03 18:07 | user | Edited: mondo + 2026-08-03 18:08 | AnjaliRH | Cross-reference review: confirmed SNOMED 191306005; confirmed OMOP 4101602; confirmed DOID 11123 2026-08-03 18:43 | AnjaliRH | Cross-reference review: confirmed SNOMED 191306005; confirmed OMOP 4101602; confirmed DOID 11123 2026-08-07 20:34 | user | Edited: mesh 2026-08-07 20:38 | AnjaliRH | Cross-reference review: confirmed SNOMED 191306005; confirmed OMOP 4101602; confirmed DOID 11123; confirmed OMIM null - 761 2026-08-07 20:40 | user | Edited: orphanet - 0019167 - 2026-08-07 20:42 | user | Edited: mondo 2026-08-07 20:42 | AnjaliRH | Cross-reference review: confirmed SNOMED 191306005; confirmed OMOP 4101602; confirmed DOID 11123; confirmed OMIM null + 2026-08-07 20:42 | user | Edited: mondo + 2026-08-10 14:32 | AnjaliRH | Cross-reference review: confirmed SNOMED 191306005; confirmed OMOP 4101602; confirmed DOID 11123; confirmed OMIM null; confirmed UMLS C0034152 + 761 + 0019167 @@ -11562,13 +12023,21 @@ At this time, not all IgG4 diseases are documented, and many are very rare. Howe 2024-09 IGG4 2026-06-15 10:37 | Importer | Imported from ARI core reports + 2026-08-03 18:01 | AnjaliRH | Cross-reference review: flagged DOID 0080356 + 2026-08-03 18:07 | user | Edited: mondo + 2026-08-03 18:08 | AnjaliRH | Cross-reference review: flagged DOID 0080356 2026-08-03 18:43 | AnjaliRH | Cross-reference review: flagged DOID 0080356 - D000077733 2026-08-07 20:35 | user | Edited: mesh 2026-08-07 20:38 | AnjaliRH | Cross-reference review: flagged DOID 0080356 2026-08-07 20:42 | AnjaliRH | Cross-reference review: flagged DOID 0080356 + 2026-08-10 14:14 | user | Edited: icd10 + 2026-08-10 14:31 | user | Edited: umls + 2026-08-10 14:32 | AnjaliRH | Cross-reference review: flagged DOID 0080356 + D000077733 10743271000119103 36717255 + D89.84 + C4087124 @@ -11588,11 +12057,16 @@ At this time, not all IgG4 diseases are documented, and many are very rare. Howe IgG4-related ophthalmic disease 2.1 2026-06-15 10:37 | Importer | Imported from ARI core reports + 2026-08-03 18:01 | AnjaliRH | Cross-reference review: confirmed SNOMED 1187510006; confirmed OMOP 37162346 + 2026-08-03 18:08 | AnjaliRH | Cross-reference review: confirmed SNOMED 1187510006; confirmed OMOP 37162346 2026-08-03 18:43 | AnjaliRH | Cross-reference review: confirmed SNOMED 1187510006; confirmed OMOP 37162346 2026-08-07 20:38 | AnjaliRH | Cross-reference review: confirmed SNOMED 1187510006; confirmed OMOP 37162346; confirmed MESH null - 449563 2026-08-07 20:40 | user | Edited: orphanet 2026-08-07 20:42 | AnjaliRH | Cross-reference review: confirmed SNOMED 1187510006; confirmed OMOP 37162346; confirmed MESH null + 2026-08-10 14:31 | user | Edited: umls + 2026-08-10 14:32 | AnjaliRH | Cross-reference review: confirmed SNOMED 1187510006; confirmed OMOP 37162346; confirmed MESH null + 449563 + C5569009 @@ -11614,7 +12088,6 @@ At this time, not all IgG4 diseases are documented, and many are very rare. Howe 3429 C0238190 G72.41 - 359.71 D018979 C84786 4216406 @@ -11644,15 +12117,19 @@ At this time, not all IgG4 diseases are documented, and many are very rare. Howe 2024-09 IBM 2026-06-15 10:37 | Importer | Imported from ARI core reports + 2026-08-03 18:01 | AnjaliRH | Cross-reference review: confirmed SNOMED 72315009; confirmed OMOP 4216406; confirmed DOID 3429 + 2026-08-03 18:04 | user | Edited: mondo + 2026-08-03 18:08 | AnjaliRH | Cross-reference review: confirmed SNOMED 72315009; confirmed OMOP 4216406; confirmed DOID 3429 2026-08-03 18:43 | AnjaliRH | Cross-reference review: confirmed SNOMED 72315009; confirmed OMOP 4216406; confirmed DOID 3429 - 147421 2026-08-07 20:37 | user | Edited: omim 2026-08-07 20:38 | AnjaliRH | Cross-reference review: confirmed SNOMED 72315009; confirmed OMOP 4216406; confirmed DOID 3429; confirmed MESH D018979 - 611 2026-08-07 20:40 | user | Edited: orphanet - 0007827 - 2026-08-07 20:42 | user | Edited: mondo 2026-08-07 20:42 | AnjaliRH | Cross-reference review: confirmed SNOMED 72315009; confirmed OMOP 4216406; confirmed DOID 3429; confirmed MESH D018979 + 2026-08-07 20:42 | user | Edited: mondo + 2026-08-10 14:32 | AnjaliRH | Cross-reference review: confirmed SNOMED 72315009; confirmed OMOP 4216406; confirmed DOID 3429; confirmed MESH D018979; confirmed ICD10 G72.41, 359.71; confirmed UMLS C0238190 + 147421 + 611 + 0007827 @@ -11727,11 +12204,15 @@ At this time, not all IgG4 diseases are documented, and many are very rare. Howe Autoimmune 2 2026-06-15 10:37 | Importer | Imported from ARI core reports + 2026-08-03 18:01 | AnjaliRH | Cross-reference review: confirmed SNOMED 24526004; confirmed OMOP 4074815; confirmed DOID 0050589 + 2026-08-03 18:04 | user | Edited: mondo + 2026-08-03 18:08 | AnjaliRH | Cross-reference review: confirmed SNOMED 24526004; confirmed OMOP 4074815; confirmed DOID 0050589 2026-08-03 18:43 | AnjaliRH | Cross-reference review: confirmed SNOMED 24526004; confirmed OMOP 4074815; confirmed DOID 0050589 2026-08-07 20:38 | AnjaliRH | Cross-reference review: confirmed SNOMED 24526004; confirmed OMOP 4074815; confirmed DOID 0050589; confirmed MESH D015212 - 0005265 - 2026-08-07 20:42 | user | Edited: mondo 2026-08-07 20:42 | AnjaliRH | Cross-reference review: confirmed SNOMED 24526004; confirmed OMOP 4074815; confirmed DOID 0050589; confirmed MESH D015212 + 2026-08-07 20:42 | user | Edited: mondo + 2026-08-10 14:32 | AnjaliRH | Cross-reference review: confirmed SNOMED 24526004; confirmed OMOP 4074815; confirmed DOID 0050589; confirmed MESH D015212; confirmed UMLS C0021390 + 0005265 @@ -11748,13 +12229,17 @@ At this time, not all IgG4 diseases are documented, and many are very rare. Howe Hirata syndrome 2.1 2026-06-15 10:37 | Importer | Imported from ARI core reports + 2026-08-03 18:01 | AnjaliRH | Cross-reference review: confirmed SNOMED 408539000; confirmed OMOP 4252384; confirmed DOID 0040100 + 2026-08-03 18:04 | user | Edited: mondo + 2026-08-03 18:08 | AnjaliRH | Cross-reference review: confirmed SNOMED 408539000; confirmed OMOP 4252384; confirmed DOID 0040100 2026-08-03 18:43 | AnjaliRH | Cross-reference review: confirmed SNOMED 408539000; confirmed OMOP 4252384; confirmed DOID 0040100 2026-08-07 20:38 | AnjaliRH | Cross-reference review: confirmed SNOMED 408539000; confirmed OMOP 4252384; confirmed DOID 0040100; confirmed MESH null - 411593 2026-08-07 20:40 | user | Edited: orphanet - 0018465 - 2026-08-07 20:42 | user | Edited: mondo 2026-08-07 20:42 | AnjaliRH | Cross-reference review: confirmed SNOMED 408539000; confirmed OMOP 4252384; confirmed DOID 0040100; confirmed MESH null + 2026-08-07 20:42 | user | Edited: mondo + 2026-08-10 14:32 | AnjaliRH | Cross-reference review: confirmed SNOMED 408539000; confirmed OMOP 4252384; confirmed DOID 0040100; confirmed MESH null; confirmed UMLS C0854359 + 411593 + 0018465 @@ -11773,9 +12258,16 @@ At this time, not all IgG4 diseases are documented, and many are very rare. Howe Type B insulin resistance syndrome 2.1 2026-06-15 10:37 | Importer | Imported from ARI core reports + 2026-08-03 18:01 | AnjaliRH | Cross-reference review: confirmed SNOMED 237652003; confirmed OMOP 4129525 + 2026-08-03 18:08 | AnjaliRH | Cross-reference review: confirmed SNOMED 237652003; confirmed OMOP 4129525 2026-08-03 18:43 | AnjaliRH | Cross-reference review: confirmed SNOMED 237652003; confirmed OMOP 4129525 2026-08-07 20:38 | AnjaliRH | Cross-reference review: confirmed SNOMED 237652003; confirmed OMOP 4129525 2026-08-07 20:42 | AnjaliRH | Cross-reference review: confirmed SNOMED 237652003; confirmed OMOP 4129525 + 2026-08-10 14:10 | user | Edited: icd10 + 2026-08-10 14:30 | user | Edited: umls + 2026-08-10 14:32 | AnjaliRH | Cross-reference review: confirmed SNOMED 237652003; confirmed OMOP 4129525 + E88.818 + C0342337 @@ -11824,13 +12316,17 @@ There are other forms of uveitis that can be autoimmune. 2024-09 IU 2026-06-15 10:37 | Importer | Imported from ARI core reports + 2026-08-03 18:01 | AnjaliRH | Cross-reference review: confirmed DOID 12732 + 2026-08-03 18:03 | user | Edited: mondo + 2026-08-03 18:08 | AnjaliRH | Cross-reference review: confirmed DOID 12732 2026-08-03 18:43 | AnjaliRH | Cross-reference review: confirmed DOID 12732; confirmed NCI C35110 2026-08-07 20:38 | AnjaliRH | Cross-reference review: confirmed DOID 12732; confirmed NCI C35110; confirmed MESH D015867 - 279914 2026-08-07 20:39 | user | Edited: orphanet - 0006806 - 2026-08-07 20:42 | user | Edited: mondo 2026-08-07 20:42 | AnjaliRH | Cross-reference review: confirmed DOID 12732; confirmed NCI C35110; confirmed MESH D015867 + 2026-08-07 20:42 | user | Edited: mondo + 2026-08-10 14:32 | AnjaliRH | Cross-reference review: confirmed DOID 12732; confirmed NCI C35110; confirmed MESH D015867; confirmed UMLS C0042166 + 279914 + 0006806 314429009 4197155 @@ -11902,13 +12398,17 @@ There are other forms of uveitis that can be autoimmune. Autoimmune 2 2026-06-15 10:37 | Importer | Imported from ARI core reports + 2026-08-03 18:01 | AnjaliRH | Cross-reference review: confirmed SNOMED 233703007; confirmed OMOP 4119786; confirmed DOID 3082 + 2026-08-03 18:03 | user | Edited: mondo + 2026-08-03 18:08 | AnjaliRH | Cross-reference review: confirmed SNOMED 233703007; confirmed OMOP 4119786; confirmed DOID 3082 2026-08-03 18:43 | AnjaliRH | Cross-reference review: confirmed SNOMED 233703007; confirmed OMOP 4119786; confirmed DOID 3082; confirmed NCI C164315 2026-08-07 20:38 | AnjaliRH | Cross-reference review: confirmed SNOMED 233703007; confirmed OMOP 4119786; confirmed DOID 3082; confirmed NCI C164315; confirmed MESH D017563 - 182095 2026-08-07 20:39 | user | Edited: orphanet - 0015925 2026-08-07 20:41 | user | Edited: mondo 2026-08-07 20:42 | AnjaliRH | Cross-reference review: confirmed SNOMED 233703007; confirmed OMOP 4119786; confirmed DOID 3082; confirmed NCI C164315; confirmed MESH D017563 + 2026-08-10 14:32 | AnjaliRH | Cross-reference review: confirmed SNOMED 233703007; confirmed OMOP 4119786; confirmed DOID 3082; confirmed NCI C164315; confirmed MESH D017563; confirmed ICD10 J84.9; confirmed UMLS C0206062 + 182095 + 0015925 @@ -11931,10 +12431,6 @@ There are other forms of uveitis that can be autoimmune. C0157917 C0157918 C0157916 - 714.33 - 714.32 - 714.3 - 714.31 M08.4 C26979 C61279 @@ -12039,7 +12535,6 @@ Some patients experience full relief from symptoms with medical attention, while 9201 C0023646 L43 - 697.0 D008010 C3189 132703 @@ -12154,7 +12649,6 @@ Most papers on lichen planus assume all cases of the disease are autoimmune or d 25674000 13477 C0152460 - 607.81 C3523 619430, 4119189 895454001, 25674000 @@ -13604,7 +14098,6 @@ It is under debate whether collagenous and lymphocytic colitis are different pha 10439 C0155072 H16.05 - 370.07 435271 22440001 Mooren's Ulcer is a chronic eye condition that causes inflammation where the eye's covering (cornea) joins with the white part of the eye (sclera). This type of inflammation is called Peripheral Ulcerative Keratitis (PUK). These persistent peripheral ulcers of the cornea often spread into and around the eye. There are several variants of this disorder: Aggressive Bilateral Mooren's Ulcers patients usually have an ulcer in one eye and congestion or discharge in the other eye. Pain is milder, and grey patches may develop within 2 mm of the border between the cornea and the white of the eye (limbus). Bilateral Indolent Mooren's Ulcers affect both eyes, with one eye typically showing more severity. Discomfort may occur with minimal inflammation. Unilateral Mooren's ulcers can occur in one or both eyes and is excessively painful. Redness and congestion are apparent, but inflammation is seen within 3 mm of the limbus. Mooren's Ulcer is believed to be an autoimmune disorder, but more research is needed. The condition can be benign, with few symptoms and low risk of complications, or malignant, with severe symptoms. Without medical care, malignant cases may lead to vision loss, but treatments are available to prevent this. @@ -13722,7 +14215,6 @@ It is under debate whether collagenous and lymphocytic colitis are different pha 8472 C0036420 L94.0 - 701.0 D012594 C72069 441928, 4066845 @@ -13898,7 +14390,6 @@ There is no cure for morphea, but treatments are available to manage symptoms. 13099 C0026654 I67.5 - 437.5 D009072 C84895 378774 @@ -14009,19 +14500,14 @@ Although this rare disease most commonly affects children, adults may have this Multiple sclerosis false ARI:0001135 - 128460000 - 426373005 - 428700003 - 49692006 24700007 2377 C0026769 - 340 G35 D009103 C3243 - 374919, 4178929, 4145049, 376970, 4027727 - 24700007, 428700003, 426373005, 49692006, 128460000 + 4027727 + 24700007 Multiple Sclerosis (MS) is a central nervous system disease that occurs when the immune system attacks the myelin, which is a protective covering around the nerves. The nerves may then suffer permanent damage. The cause of the abnormal immune system action is unknown, but there seems to be some genetic link. The most common form of MS is relapsing-remitting which occurs when a patient has symptom-free periods, but the patient may develop a progressive form where the symptoms worsen over time. Women are affected twice as often as men. MS varies in severity, with some people losing the ability to walk. Disseminated sclerosis MS @@ -14055,6 +14541,10 @@ Although this rare disease most commonly affects children, adults may have this 2024-09 MS 2026-06-15 10:37 | Importer | Imported from ARI core reports + 2026-08-24 16:36 | aaronabend | Cross-reference review: confirmed DOID 2377; confirmed MONDO 0005301; confirmed NCI C3243; confirmed SNOMED 128460000, 426373005, 428700003, 49692006, 24700007; confirmed OMOP 374919, 4178929, 4145049, 376970, 4027727 + 2026-08-27 17:57 | aaronabend | Cross-reference review: confirmed DOID 2377; confirmed MONDO 0005301; confirmed NCI C3243; confirmed SNOMED 128460000, 426373005, 428700003, 49692006, 24700007; confirmed OMOP 374919, 4178929, 4145049, 376970, 4027727 + 2026-08-27 17:57 | aaronabend | Cross-reference review: confirmed DOID 2377; confirmed MONDO 0005301; confirmed NCI C3243; confirmed SNOMED 24700007; confirmed OMOP 4027727 + 0005301 @@ -14195,10 +14685,8 @@ Although this rare disease most commonly affects children, adults may have this 437 C0026896 C1260409 - 358.0 G70.0 G70.00 - 358.00 D009157 C60989 76685 @@ -14918,7 +15406,6 @@ The specific location of vasculitis inflammation determines what tissue or organ 25044007 8869 C0027873 - 341.0 G36.0 D009471 C84934 @@ -14952,6 +15439,12 @@ The specific location of vasculitis inflammation determines what tissue or organ 2024-09 NMO 2026-06-15 10:37 | Importer | Imported from ARI core reports + 2026-08-17 18:32 | aaronabend | Cross-reference review: confirmed SNOMED 25044007; confirmed OMOP 380995; confirmed DOID 8869; confirmed MONDO 0019100; confirmed NCI C84934; confirmed ICD10 G36.0; confirmed ORPHANET 71211; confirmed MESH D009471; no term in OMIM + 2026-08-24 16:36 | aaronabend | Cross-reference review: confirmed SNOMED 25044007; confirmed OMOP 380995; confirmed DOID 8869; confirmed MONDO 0019100; confirmed NCI C84934; confirmed ICD10 G36.0; confirmed ORPHANET 71211; confirmed MESH D009471; no term in OMIM + 2026-08-27 17:57 | aaronabend | Cross-reference review: confirmed SNOMED 25044007; confirmed OMOP 380995; confirmed DOID 8869; confirmed MONDO 0019100; confirmed NCI C84934; confirmed ICD10 G36.0; confirmed ORPHANET 71211; confirmed MESH D009471; no term in OMIM + 2026-08-27 17:57 | aaronabend | Cross-reference review: confirmed SNOMED 25044007; confirmed OMOP 4027727; confirmed DOID 8869; confirmed MONDO 0019100; confirmed NCI C84934; confirmed ICD10 G36.0; confirmed ORPHANET 71211; confirmed MESH D009471; no term in OMIM + 0019100 + 71211 @@ -15441,9 +15934,7 @@ Patients with GO experience swelling in the tissues, muscles, and fat in the eye 1166 C0158178 C0085574 - 719.3 M12.3 - 719.31 C538103 76196 50442003 @@ -15946,7 +16437,6 @@ Patients with GO experience swelling in the tissues, muscles, and fat in the eye 9182 C0030807 L10 - 694.4 D010392 C34909 4262682, 4066821, 135338, 4279526, 4148690, 4291435, 4170723 @@ -16163,7 +16653,6 @@ Pemphigus is different from bullous pemphigoid, a blistering skin condition that 155441006 9810 C0031036 - 446.0 M30.0 D010488 C26847 @@ -16873,7 +17362,6 @@ Pemphigus is different from bullous pemphigoid, a blistering skin condition that 853 C0032533 M35.3 - 725 D011111 C85018 255348 @@ -17141,7 +17629,6 @@ Pemphigus is different from bullous pemphigoid, a blistering skin condition that 10507 C0152107 I24.1 - 411.0 37311078, 319038, 4239311, 4150305 827164008, 66189004, 58600007, 278536002 All of the conditions listed here occur following a heart attack, traumatic injury to the heart or the pericardium, or an operation such as coronary artery bypass grafting (CABG), mitral valve replacement, aortic valve replacement, and pacemaker or stent implantation. @@ -17284,7 +17771,6 @@ To date, there is no direct or indirect evidence that post-pericardiotomy syndro 12236 C0023892 C0008312 - 571.6 K74.3 K74.5 D008105 @@ -17934,7 +18420,6 @@ The development of psoriasis involves a complex cycle of immune activation and s 9008 C0003872 L40.5 - 696.0 D015535 C61277 81931, 40319772 @@ -18142,7 +18627,6 @@ A third type of PRCA, Diamond-Blackfan syndrome, is due to genetic mutation and 8553 C0085652 L88 - 686.01 D017511 133283 74578003 @@ -18295,7 +18779,6 @@ A third type of PRCA, Diamond-Blackfan syndrome, is due to genetic mutation and 10300 C0034734 I73.0 - 443.0 D011928 4143972, 4229162 356198000, 266261006 @@ -18401,9 +18884,7 @@ Secondary Raynaud's is a symptom experienced (and reported) by patients with aut 6196 C0035012 C0152085 - 099.3 M02.10 - 711.30 M02.3 D016918 C34975 @@ -18712,7 +19193,6 @@ In cases where the cartilage is not visible, RP can cause heart valve abnormalit 32914008 0050425 C0035258 - 333.94 G25.81 D012148 C84501 @@ -19071,10 +19551,7 @@ Since antibiotics have reduced the incidence of rheumatic fever, the incidence o 1586 C0035436 C0264743 - I00-I02 I00 - 390-392.99 - 390 D012213 C34984 442313 @@ -19243,7 +19720,6 @@ Note: scarlet fever is another symptom of a strep infection but is not a separat 69896004 7148 C0003873 - 714.0 M06.9 D001172 C2884 @@ -19542,7 +20018,6 @@ There is no cure, though treatments to manage symptoms are available. Prognosis 72470008 11335 C0036202 - 135 D86 D012507 C34995 @@ -19850,7 +20325,6 @@ Patients with Schnitzler syndrome typically experience chronic rash, relapsing f 13452 C0036416 H15.0 - 379.00 D015423 C119046 434944 @@ -20626,7 +21100,6 @@ Patients with Schnitzler syndrome typically experience chronic rash, relapsing f 13366 C0085292 G25.82 - 333.91 D016750 C85170 379008 @@ -20865,7 +21338,6 @@ This condition most frequently occurs following surgery to a region of the body 75315001 12029 C0029077 - 360.11 H44.13 D009879 438739 @@ -20986,7 +21458,6 @@ This condition most frequently occurs following surgery to a region of the body 55464009 9074 C0024141 - 710.0 M32.9 D008180 C3201 @@ -21284,7 +21755,6 @@ When mastocytosis is limited to the skin, it is called cutaneous mastocytosis, a 89155008 418 C0036421 - 710.1 M34.0 D012595 C72070 @@ -21638,7 +22108,6 @@ To be diagnosed with CREST, you must have 3 out of the 5 symptoms.2508 C0003490 C0039263 - 446.7 M31.4 D001015 D013625 @@ -21788,7 +22257,6 @@ Early symptoms may include fever, night sweats, fatigue, joint pain, and chest d 400130008 13375 C0039483 - 446.5 D013700 C35065 4290976 @@ -22269,9 +22737,7 @@ Early symptoms may include fever, night sweats, fatigue, joint pain, and chest d 8577 C0009324 C0375359 - 556.5 K51 - 556 D003093 C2952 81893 @@ -22824,7 +23290,6 @@ The most common form of autoimmune uveitis is intermediate uveitis.12306 C0042900 L80 - 709.01 D014820 C26915 138502 @@ -22907,7 +23372,6 @@ Normally, the color of hair, skin, and eyes is determined by melanin. Vitiligo o 193497004 12297 C0042170 - 364.24 H20.82 D014607 C85218 @@ -23149,6 +23613,7 @@ Some cases of this disease are caused by medications and are not autoimmune.2026-08-03 18:14 | user | Edited: mesh 2026-08-03 18:15 | KrishnaTO | Cross-reference review: flagged SNOMED 62382002 2026-08-12 01:11 | KrishnaTO | Cross-reference review: flagged SNOMED 62382002 + 2026-08-15 22:37 | KrishnaTO | Cross-reference review: flagged SNOMED 62382002